MNTP_ACET2
ID MNTP_ACET2 Reviewed; 198 AA.
AC A3DFC2;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=Cthe_1420;
OS Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC
OS 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) (Clostridium thermocellum).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Oscillospiraceae;
OC Acetivibrio.
OX NCBI_TaxID=203119;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL
RC B-4536 / VPI 7372;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Wu J.H.D.,
RA Newcomb M., Richardson P.;
RT "Complete sequence of Clostridium thermocellum ATCC 27405.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000568; ABN52651.1; -; Genomic_DNA.
DR RefSeq; WP_003518316.1; NC_009012.1.
DR AlphaFoldDB; A3DFC2; -.
DR STRING; 203119.Cthe_1420; -.
DR EnsemblBacteria; ABN52651; ABN52651; Cthe_1420.
DR KEGG; cth:Cthe_1420; -.
DR eggNOG; COG1971; Bacteria.
DR HOGENOM; CLU_096410_3_0_9; -.
DR OMA; NKEREFA; -.
DR OrthoDB; 1857762at2; -.
DR Proteomes; UP000002145; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Manganese; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..198
FT /note="Putative manganese efflux pump MntP"
FT /id="PRO_0000296922"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 37..57
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 131..153
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 198 AA; 21447 MW; 0B05FED59F585864 CRC64;
MSSIELLIIA VGLSMDAFAV AICKGLSMKK MSYRNAVLTG CFFGGFQALM PLLGYLLGTQ
FKDYITSIDH WIAFGLLSLI GINMIKESKN TCEITDEDDT FSLKSLTVMA FATSIDALAI
GVTFAFLQVN IIPAVTMIGI TTFTFSFLGV KIGNLFGVKF QSKAEIVGGL ILIGMGCKIL
FDHLGVISFV FDSLNKFN
