ID   MNTP_CARHZ              Reviewed;         180 AA.
AC   Q3A931;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN   Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=CHY_2560;
OS   Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 /
OS   Z-2901).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Carboxydothermus.
OX   NCBI_TaxID=246194;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-161 / DSM 6008 / Z-2901;
RX   PubMed=16311624; DOI=10.1371/journal.pgen.0010065;
RA   Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J.,
RA   Madupu R., Sullivan S.A., Kolonay J.F., Nelson W.C., Tallon L.J.,
RA   Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B., Robb F.T., Eisen J.A.;
RT   "Life in hot carbon monoxide: the complete genome sequence of
RT   Carboxydothermus hydrogenoformans Z-2901.";
RL   PLoS Genet. 1:563-574(2005).
CC   -!- FUNCTION: Probably functions as a manganese efflux pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01521}.
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DR   EMBL; CP000141; ABB14970.1; -; Genomic_DNA.
DR   RefSeq; WP_011345426.1; NC_007503.1.
DR   AlphaFoldDB; Q3A931; -.
DR   STRING; 246194.CHY_2560; -.
DR   EnsemblBacteria; ABB14970; ABB14970; CHY_2560.
DR   KEGG; chy:CHY_2560; -.
DR   eggNOG; COG1971; Bacteria.
DR   HOGENOM; CLU_096410_1_1_9; -.
DR   OMA; WHFGLFQ; -.
DR   OrthoDB; 1857762at2; -.
DR   Proteomes; UP000002706; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01521; MntP_pump; 1.
DR   InterPro; IPR003810; Mntp/YtaF.
DR   InterPro; IPR022929; Put_MntP.
DR   PANTHER; PTHR35529; PTHR35529; 1.
DR   Pfam; PF02659; Mntp; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Manganese; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..180
FT                   /note="Putative manganese efflux pump MntP"
FT                   /id="PRO_0000296917"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ   SEQUENCE   180 AA;  19299 MW;  6C983512F051D1EA CRC64;
     MSLWEIFLLA VALGTDSFSL CVGLGMGKIK RKEIIALSLT VLVYHIVMPI LGWFAGDLTG
     RFLGKVATYI GGAILIYLGY KMIRHGISQE EELPHVTYNL VGLLLIGLSV SMDALSVGFT
     LGTVKVNLWF VALITGIVAG VMTLSGLLLG RRVSKVLGER AQIVGGLILL LIAGKLIFRG