MNTP_CLOP1
ID MNTP_CLOP1 Reviewed; 213 AA.
AC Q0TTS0;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=CPF_0516;
OS Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB
OS 6125 / NCTC 8237 / Type A).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=195103;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / S 107 /
RC Type A;
RX PubMed=16825665; DOI=10.1101/gr.5238106;
RA Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T.,
RA Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H.,
RA Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D.,
RA Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J.,
RA Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B.,
RA Paulsen I.T.;
RT "Skewed genomic variability in strains of the toxigenic bacterial pathogen,
RT Clostridium perfringens.";
RL Genome Res. 16:1031-1040(2006).
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
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DR EMBL; CP000246; ABG84757.1; -; Genomic_DNA.
DR RefSeq; WP_011590238.1; NC_008261.1.
DR AlphaFoldDB; Q0TTS0; -.
DR STRING; 195103.CPF_0516; -.
DR EnsemblBacteria; ABG84757; ABG84757; CPF_0516.
DR GeneID; 29572359; -.
DR KEGG; cpf:CPF_0516; -.
DR eggNOG; COG1971; Bacteria.
DR HOGENOM; CLU_096410_3_0_9; -.
DR OMA; NKEREFA; -.
DR OrthoDB; 1857762at2; -.
DR Proteomes; UP000001823; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Manganese; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..213
FT /note="Putative manganese efflux pump MntP"
FT /id="PRO_0000296920"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 213 AA; 23084 MW; 9EEE8D5157E1FD0C CRC64;
MSILSIVLTG FGLAMDAFAV SVAKGITLTR VKAKDALKVA LFFGGFQALM PLIGWGAGRY
FADYIKAFDH WIAFILLGFI GGKMIFEALK EDDEEKAEVA VSMEVSKNKE REFANMKRKE
ELSAKNLTVL AIATSIDALA VGVSFAFLGI SIVQTIIIIG IITFVLCFLG VIIGEKLGDI
FKNYAEIVGG VILILIGINI LLEHTGIIEK LFS
