MNTP_GEOTN
ID MNTP_GEOTN Reviewed; 183 AA.
AC A4ITK4;
DT 24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=GTNG_3319;
OS Geobacillus thermodenitrificans (strain NG80-2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX NCBI_TaxID=420246;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NG80-2;
RX PubMed=17372208; DOI=10.1073/pnas.0609650104;
RA Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X.,
RA Han W., Peng X., Liu R., Wang L.;
RT "Genome and proteome of long-chain alkane degrading Geobacillus
RT thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
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DR EMBL; CP000557; ABO68658.1; -; Genomic_DNA.
DR RefSeq; WP_008880708.1; NC_009328.1.
DR AlphaFoldDB; A4ITK4; -.
DR STRING; 420246.GTNG_3319; -.
DR EnsemblBacteria; ABO68658; ABO68658; GTNG_3319.
DR KEGG; gtn:GTNG_3319; -.
DR eggNOG; COG1971; Bacteria.
DR HOGENOM; CLU_096410_1_0_9; -.
DR OMA; WHFGLFQ; -.
DR OrthoDB; 1857762at2; -.
DR Proteomes; UP000001578; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Manganese; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..183
FT /note="Putative manganese efflux pump MntP"
FT /id="PRO_0000296929"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 183 AA; 19670 MW; C52848364CA573EF CRC64;
MGALIGEMIA LSLMALALGM DAFSVALGMG LLRLRLRQIF YIGLTIGLFH IFMPLVGMAV
GRFLSREFGS IATYAGGVLL LWLGGQMIVT SFQQEEGTSF LPHGAGLLFF AFSVSLDSFS
VGLSLGIFGA RTMATILLFG LFSTVLTWIG LLVGRHFRQW LGSYSEALGG SILLVFGLKL
LFS