MNTP_KLEP7
ID MNTP_KLEP7 Reviewed; 188 AA.
AC A6TAZ2;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 2.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN OrderedLocusNames=KPN78578_23020; ORFNames=KPN_02337;
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578;
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01521}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABR77763.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000647; ABR77763.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_002910921.1; NC_009648.1.
DR AlphaFoldDB; A6TAZ2; -.
DR STRING; 272620.KPN_02337; -.
DR EnsemblBacteria; ABR77763; ABR77763; KPN_02337.
DR KEGG; kpn:KPN_02337; -.
DR HOGENOM; CLU_096410_0_0_6; -.
DR OMA; WHFGLFQ; -.
DR Proteomes; UP000000265; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Manganese; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..188
FT /note="Putative manganese efflux pump MntP"
FT /id="PRO_0000315567"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 107..129
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 188 AA; 19903 MW; DAFE2663D5D7A97F CRC64;
MNLSATILLA FGMSMDAFAA SIGKGATLHK PKFSEAVRTG LIFGAIETLT PLVGWGLGML
ASQFILEWNH WIAFILLVFL GGRMIVEGFR GDSDEACEAP HRHGFWLLVT TAFATSLDAM
AVGVGLAFLQ VSIVTTALAI GCATFIMSTL GMMVGRFIGP LLGKRAEILG GIVLIGIGSE
ILWSHFAG