MNTP_METB6
ID MNTP_METB6 Reviewed; 185 AA.
AC A7I5W4;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=Mboo_0607;
OS Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX NCBI_TaxID=456442;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21154 / JCM 14090 / 6A8;
RX PubMed=25998264; DOI=10.1099/mic.0.000117;
RA Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT peatland environments.";
RL Microbiology 161:1572-1581(2015).
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
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DR EMBL; CP000780; ABS55125.1; -; Genomic_DNA.
DR RefSeq; WP_012106146.1; NC_009712.1.
DR AlphaFoldDB; A7I5W4; -.
DR STRING; 456442.Mboo_0607; -.
DR EnsemblBacteria; ABS55125; ABS55125; Mboo_0607.
DR GeneID; 5412167; -.
DR KEGG; mbn:Mboo_0607; -.
DR eggNOG; arCOG04898; Archaea.
DR HOGENOM; CLU_096410_3_0_2; -.
DR OMA; WHFGLFQ; -.
DR OrthoDB; 106751at2157; -.
DR Proteomes; UP000002408; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Manganese; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..185
FT /note="Putative manganese efflux pump MntP"
FT /id="PRO_1000068637"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 185 AA; 19218 MW; 4590706F40597525 CRC64;
MDLLTSSLIG IGLSMDCFAV ALAIGTSERL PLVRSALVIA ASFGIFQAGM TIAGWIAGAS
LYTEISSYGS WIAFLLLAGI GIKMIYDGIR EEHEPTLSGL HAIPVILLSL ATSIDAFAAG
VSFGVLGSTV LMPALAIGLV CFVVSCAGVF CGMRLEKLLG NRTEIFGGVI LILIGIQILT
DILPL