ID   MNTP_METLZ              Reviewed;         185 AA.
AC   A2SPZ1;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN   Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=Mlab_0221;
OS   Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX   NCBI_TaxID=410358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43576 / DSM 4855 / Z;
RX   PubMed=21304657; DOI=10.4056/sigs.35575;
RA   Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL   Stand. Genomic Sci. 1:197-203(2009).
CC   -!- FUNCTION: Probably functions as a manganese efflux pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01521}.
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DR   EMBL; CP000559; ABN06397.1; -; Genomic_DNA.
DR   RefSeq; WP_011832598.1; NC_008942.1.
DR   AlphaFoldDB; A2SPZ1; -.
DR   STRING; 410358.Mlab_0221; -.
DR   EnsemblBacteria; ABN06397; ABN06397; Mlab_0221.
DR   GeneID; 4795668; -.
DR   KEGG; mla:Mlab_0221; -.
DR   eggNOG; arCOG04898; Archaea.
DR   HOGENOM; CLU_096410_3_0_2; -.
DR   OMA; WHFGLFQ; -.
DR   OrthoDB; 106751at2157; -.
DR   Proteomes; UP000000365; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01521; MntP_pump; 1.
DR   InterPro; IPR003810; Mntp/YtaF.
DR   InterPro; IPR022929; Put_MntP.
DR   PANTHER; PTHR35529; PTHR35529; 1.
DR   Pfam; PF02659; Mntp; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Manganese; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..185
FT                   /note="Putative manganese efflux pump MntP"
FT                   /id="PRO_0000292548"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ   SEQUENCE   185 AA;  19464 MW;  CA3A093501FAAC65 CRC64;
     MTDLLLSSLV IAVGLAMDSF SVSLAGGAAL KDNIVKTAVT AGIFFGFFQF AMPLLGWGIG
     VPITQVIDPF GYWIVVGLFF FIGGKMIWDS FSGDEEGISL IGWKVLLLLA VATSIDALAV
     GISFALIGEA VLLPAVIIGV VAFLFSFFGV LAGHKLSSIL GNKMQILGGV ILVLIGIKFL
     IEYCL