ID   MNTP_METS3              Reviewed;         184 AA.
AC   A5UJ57;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN   Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=Msm_0030;
OS   Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=420247;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35061 / DSM 861 / OCM 144 / PS;
RX   PubMed=17563350; DOI=10.1073/pnas.0704189104;
RA   Samuel B.S., Hansen E.E., Manchester J.K., Coutinho P.M., Henrissat B.,
RA   Fulton R., Latreille P., Kim K., Wilson R.K., Gordon J.I.;
RT   "Genomic and metabolic adaptations of Methanobrevibacter smithii to the
RT   human gut.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10643-10648(2007).
CC   -!- FUNCTION: Probably functions as a manganese efflux pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01521}.
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DR   EMBL; CP000678; ABQ86235.1; -; Genomic_DNA.
DR   RefSeq; WP_011953635.1; NC_009515.1.
DR   AlphaFoldDB; A5UJ57; -.
DR   STRING; 420247.Msm_0030; -.
DR   EnsemblBacteria; ABQ86235; ABQ86235; Msm_0030.
DR   GeneID; 5216282; -.
DR   KEGG; msi:Msm_0030; -.
DR   PATRIC; fig|420247.28.peg.31; -.
DR   eggNOG; arCOG04898; Archaea.
DR   HOGENOM; CLU_096410_3_0_2; -.
DR   OMA; WHFGLFQ; -.
DR   Proteomes; UP000001992; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01521; MntP_pump; 1.
DR   InterPro; IPR003810; Mntp/YtaF.
DR   InterPro; IPR022929; Put_MntP.
DR   PANTHER; PTHR35529; PTHR35529; 1.
DR   Pfam; PF02659; Mntp; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Manganese; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..184
FT                   /note="Putative manganese efflux pump MntP"
FT                   /id="PRO_0000300163"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ   SEQUENCE   184 AA;  20055 MW;  6F7DD797B2AD00C3 CRC64;
     MDTSLISIII IAIALAMDAF SVSLTKGFTQ KNLTKSQILY YGLFFGFFQF IMPVIGYICG
     TTISSFVSTV APWIAFFLLL AIGLNMIRES LDSDDEYIMD TFSFKELTLL AVATSIDAFA
     VGITFALLNM SLLLPCTIIG IVAFIFSISG IFIGKKLGNY FGDKFEILGG AVLILIGIKI
     LLGY