ID   MNTP_NEIMF              Reviewed;         188 AA.
AC   A1KRP4;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN   Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=NMC0207;
OS   Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM
OS   15464 / FAM18).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=272831;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700532 / DSM 15464 / FAM18;
RX   PubMed=17305430; DOI=10.1371/journal.pgen.0030023;
RA   Bentley S.D., Vernikos G.S., Snyder L.A.S., Churcher C., Arrowsmith C.,
RA   Chillingworth T., Cronin A., Davis P.H., Holroyd N.E., Jagels K.,
RA   Maddison M., Moule S., Rabbinowitsch E., Sharp S., Unwin L., Whitehead S.,
RA   Quail M.A., Achtman M., Barrell B.G., Saunders N.J., Parkhill J.;
RT   "Meningococcal genetic variation mechanisms viewed through comparative
RT   analysis of serogroup C strain FAM18.";
RL   PLoS Genet. 3:230-240(2007).
CC   -!- FUNCTION: Probably functions as a manganese efflux pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01521}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01521}.
CC   -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01521}.
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DR   EMBL; AM421808; CAM09523.1; -; Genomic_DNA.
DR   RefSeq; WP_002236626.1; NC_008767.1.
DR   AlphaFoldDB; A1KRP4; -.
DR   EnsemblBacteria; CAM09523; CAM09523; NMC0207.
DR   KEGG; nmc:NMC0207; -.
DR   HOGENOM; CLU_096410_0_0_4; -.
DR   OMA; WHFGLFQ; -.
DR   OrthoDB; 1857762at2; -.
DR   Proteomes; UP000002286; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01521; MntP_pump; 1.
DR   InterPro; IPR003810; Mntp/YtaF.
DR   InterPro; IPR022929; Put_MntP.
DR   PANTHER; PTHR35529; PTHR35529; 1.
DR   Pfam; PF02659; Mntp; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Manganese; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..188
FT                   /note="Putative manganese efflux pump MntP"
FT                   /id="PRO_0000296932"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        104..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ   SEQUENCE   188 AA;  19695 MW;  4C9224C93674BEE3 CRC64;
     MSLYALLLIA LGMSMDAFAV ALAKGAAVRM PPRKIAATAL VFGTVEALTP LAGWVGGFYA
     KPFISEWDHW AAFVLLGGLG LKMMHEGLSG EAEDARENKR ESWWLTVLTA FGTSIDSMIV
     GVGLAFMEVN IAFAAAIIGM ATTVLVAVGL TVGRALGVLF GRRAEFAGGL VLIAIGTWTL
     LSHLGLIG