MNTP_SALHS
ID MNTP_SALHS Reviewed; 188 AA.
AC B4TKG5;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=Probable manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; Synonyms=yebN;
GN OrderedLocusNames=SeHA_C2035;
OS Salmonella heidelberg (strain SL476).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=454169;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SL476;
RX PubMed=21602358; DOI=10.1128/jb.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01521}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
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DR EMBL; CP001120; ACF68915.1; -; Genomic_DNA.
DR RefSeq; WP_001531552.1; NC_011083.1.
DR AlphaFoldDB; B4TKG5; -.
DR KEGG; seh:SeHA_C2035; -.
DR HOGENOM; CLU_096410_0_0_6; -.
DR OMA; WHFGLFQ; -.
DR Proteomes; UP000001866; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Manganese; Membrane;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..188
FT /note="Probable manganese efflux pump MntP"
FT /id="PRO_1000200039"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 188 AA; 20065 MW; 797E3C6E435159DC CRC64;
MHYTATVLLA FGMSMDAFAA SIGKGATLHK PKFSEALRTG LIFGAVETLT PLIGWGLGIL
ASKFVLEWNH WIAFVLLIFL GGRMIIEGIR GGSDEDETPL RRHSFWLLVT TAIATSLDAM
AVGVGLAFLQ VNIIATALAI GCATLIMSTL GMMIGRFIGP MLGKRAEILG GVVLIGIGVQ
ILWTHFHG