MNTP_SALTY
ID MNTP_SALTY Reviewed; 188 AA.
AC Q8ZP00;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2004, sequence version 2.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=Probable manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; Synonyms=yebN;
GN OrderedLocusNames=STM1834;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Probably functions as a manganese efflux pump.
CC {ECO:0000255|HAMAP-Rule:MF_01521}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01521}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
CC -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC Rule:MF_01521}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL20749.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE006468; AAL20749.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_460790.1; NC_003197.2.
DR AlphaFoldDB; Q8ZP00; -.
DR STRING; 99287.STM1834; -.
DR PaxDb; Q8ZP00; -.
DR EnsemblBacteria; AAL20749; AAL20749; STM1834.
DR GeneID; 1253353; -.
DR KEGG; stm:STM1834; -.
DR PATRIC; fig|99287.12.peg.1935; -.
DR HOGENOM; CLU_096410_0_0_6; -.
DR OMA; WHFGLFQ; -.
DR PhylomeDB; Q8ZP00; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01521; MntP_pump; 1.
DR InterPro; IPR003810; Mntp/YtaF.
DR InterPro; IPR022929; Put_MntP.
DR PANTHER; PTHR35529; PTHR35529; 1.
DR Pfam; PF02659; Mntp; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Manganese; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..188
FT /note="Probable manganese efflux pump MntP"
FT /id="PRO_0000155666"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ SEQUENCE 188 AA; 20049 MW; 6BE3B363C1CCD6DC CRC64;
MHFTATVLLA FGMSMDAFAA SIGKGATLHK PKFSEALRTG LIFGAVETLT PLIGWGLGIL
ASKFVLEWNH WIAFVLLIFL GGRMIIEGIR GGSDEDETPL RRHSFWLLVT TAIATSLDAM
AVGVGLAFLQ VNIIATALAI GCATLIMSTL GMMIGRFIGP MLGKRAEILG GVVLIGIGVQ
ILWTHFHG