ID   MNTP_SYNWW              Reviewed;         195 AA.
AC   Q0AUC1;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Putative manganese efflux pump MntP {ECO:0000255|HAMAP-Rule:MF_01521};
GN   Name=mntP {ECO:0000255|HAMAP-Rule:MF_01521}; OrderedLocusNames=Swol_2394;
OS   Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC   Syntrophomonas.
OX   NCBI_TaxID=335541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2245B / Goettingen;
RX   PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA   Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA   McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT   "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT   metabolism and biohydrogen production.";
RL   Environ. Microbiol. 12:2289-2301(2010).
CC   -!- FUNCTION: Probably functions as a manganese efflux pump.
CC       {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01521};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01521}.
CC   -!- SIMILARITY: Belongs to the MntP (TC 9.B.29) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01521}.
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DR   EMBL; CP000448; ABI69683.1; -; Genomic_DNA.
DR   RefSeq; WP_011641767.1; NC_008346.1.
DR   AlphaFoldDB; Q0AUC1; -.
DR   STRING; 335541.Swol_2394; -.
DR   EnsemblBacteria; ABI69683; ABI69683; Swol_2394.
DR   KEGG; swo:Swol_2394; -.
DR   eggNOG; COG1971; Bacteria.
DR   HOGENOM; CLU_096410_1_1_9; -.
DR   OMA; WHFGLFQ; -.
DR   OrthoDB; 1857762at2; -.
DR   Proteomes; UP000001968; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01521; MntP_pump; 1.
DR   InterPro; IPR003810; Mntp/YtaF.
DR   InterPro; IPR022929; Put_MntP.
DR   PANTHER; PTHR35529; PTHR35529; 1.
DR   Pfam; PF02659; Mntp; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Manganese; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..195
FT                   /note="Putative manganese efflux pump MntP"
FT                   /id="PRO_0000296940"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01521"
SQ   SEQUENCE   195 AA;  20760 MW;  2BE2465F1C0F6C20 CRC64;
     MIEILITIIL LAIVLGMDAL SLAMGMGLRG VAKDYEKKFV LTVGILHVLM PLLGLNLGLV
     AGRFLGVWAT RLGALVLVYL GWQMLSKGYA EIQPQRYNFA EAKTILAGKQ QSTLDSWTSI
     LLLGLSVSID ALTVGFTLGT LKMPILITVL IMGLIAASMS WVGFAGGRVL GRLTGSYAQI
     LGGVVLLALA IKFVV