MNTR_SALTY
ID MNTR_SALTY Reviewed; 157 AA.
AC P67710; Q8XH22;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Transcriptional regulator MntR;
DE AltName: Full=Manganese transport regulator;
GN Name=mntR; OrderedLocusNames=STM0835;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: In the presence of manganese, represses expression of mntH
CC and mntS. Up-regulates expression of mntP (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- DOMAIN: It contains an N-terminal DNA-binding domain and a metal-
CC binding domain. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DtxR/MntR family. {ECO:0000305}.
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DR EMBL; AE006468; AAL19771.1; -; Genomic_DNA.
DR RefSeq; NP_459812.1; NC_003197.2.
DR RefSeq; WP_000533542.1; NC_003197.2.
DR AlphaFoldDB; P67710; -.
DR SMR; P67710; -.
DR STRING; 99287.STM0835; -.
DR PaxDb; P67710; -.
DR EnsemblBacteria; AAL19771; AAL19771; STM0835.
DR GeneID; 1252354; -.
DR KEGG; stm:STM0835; -.
DR PATRIC; fig|99287.12.peg.872; -.
DR HOGENOM; CLU_069532_2_0_6; -.
DR OMA; SWDAIDR; -.
DR PhylomeDB; P67710; -.
DR BioCyc; SENT99287:STM0835-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 1.10.60.10; -; 1.
DR InterPro; IPR001367; Fe_dep_repressor.
DR InterPro; IPR036421; Fe_dep_repressor_sf.
DR InterPro; IPR022687; HTH_DTXR.
DR InterPro; IPR022689; Iron_dep_repressor.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF02742; Fe_dep_repr_C; 1.
DR Pfam; PF01325; Fe_dep_repress; 1.
DR SMART; SM00529; HTH_DTXR; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF47979; SSF47979; 1.
DR PROSITE; PS50944; HTH_DTXR; 1.
PE 3: Inferred from homology;
KW Activator; Cytoplasm; DNA-binding; Manganese; Reference proteome;
KW Repressor; Transcription; Transcription regulation.
FT CHAIN 1..157
FT /note="Transcriptional regulator MntR"
FT /id="PRO_0000201113"
FT DOMAIN 34..95
FT /note="HTH dtxR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00296"
SQ SEQUENCE 157 AA; 17727 MW; 01E14972776D2A77 CRC64;
MGRRAGTPTT KKVTQLVNVE EHVEGFRQVR EAHRRELIDD YVELISDLII EVGEARQVDM
AARLGVSQPT VAKMLKRLAS LGFIQMIPWR GVFLTPEGEK LAQESRERHQ IVENFLLVLG
VSPEIARRDA EGMEHHVSQE TLDAFLAFTQ QHGTSAE
