ID   MOAB_ECO57              Reviewed;         170 AA.
AC   P0AF00; P30746;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Molybdenum cofactor biosynthesis protein B;
GN   Name=moaB; OrderedLocusNames=Z1001, ECs0860;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: May be involved in the biosynthesis of molybdopterin. Can
CC       bind GTP and has low GTPase activity. Can bind MPT, but has no MPT
CC       adenylyl transferase activity. {ECO:0000250}.
CC   -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC   -!- SIMILARITY: Belongs to the MoaB/Mog family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG55153.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34283.1; -; Genomic_DNA.
DR   PIR; D90736; D90736.
DR   PIR; E85586; E85586.
DR   RefSeq; NP_308887.1; NC_002695.1.
DR   RefSeq; WP_000084639.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AF00; -.
DR   SMR; P0AF00; -.
DR   STRING; 155864.EDL933_0903; -.
DR   EnsemblBacteria; AAG55153; AAG55153; Z1001.
DR   EnsemblBacteria; BAB34283; BAB34283; ECs_0860.
DR   GeneID; 66670947; -.
DR   GeneID; 917603; -.
DR   KEGG; ece:Z1001; -.
DR   KEGG; ecs:ECs_0860; -.
DR   PATRIC; fig|386585.9.peg.974; -.
DR   eggNOG; COG0521; Bacteria.
DR   HOGENOM; CLU_077358_2_2_6; -.
DR   OMA; TGWDGIL; -.
DR   UniPathway; UPA00344; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd00886; MogA_MoaB; 1.
DR   Gene3D; 3.40.980.10; -; 1.
DR   InterPro; IPR012245; MoaB.
DR   InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR   InterPro; IPR001453; MoaB/Mog_dom.
DR   InterPro; IPR013484; MoaB_proteobac.
DR   InterPro; IPR008284; MoCF_biosynth_CS.
DR   PANTHER; PTHR43232; PTHR43232; 1.
DR   Pfam; PF00994; MoCF_biosynth; 1.
DR   PIRSF; PIRSF006443; MoaB; 1.
DR   SMART; SM00852; MoCF_biosynth; 1.
DR   SUPFAM; SSF53218; SSF53218; 1.
DR   TIGRFAMs; TIGR02667; moaB_proteo; 1.
DR   TIGRFAMs; TIGR00177; molyb_syn; 1.
DR   PROSITE; PS01078; MOCF_BIOSYNTHESIS_1; 1.
PE   3: Inferred from homology;
KW   GTP-binding; Molybdenum cofactor biosynthesis; Nucleotide-binding;
KW   Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..170
FT                   /note="Molybdenum cofactor biosynthesis protein B"
FT                   /id="PRO_0000170971"
FT   BINDING         110
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   170 AA;  18665 MW;  C9AA21A7E12E53B0 CRC64;
     MSQVSTEFIP TRIAILTVSN RRGEEDDTSG HYLRDSAQEA GHHVVDKAIV KENRYAIRAQ
     VSAWIASDDV QVVLITGGTG LTEGDQAPEA LLPLFDREVE GFGEVFRMLS FEEIGTSTLQ
     SRAVAGVANK TLIFAMPGST KACRTAWENI IAPQLDARTR PCNFHPHLKK