ID   MOAR_KLEAE              Reviewed;         227 AA.
AC   P54794;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Monoamine regulon transcriptional regulator;
GN   Name=moaR;
OS   Klebsiella aerogenes (Enterobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W70;
RX   PubMed=8407801; DOI=10.1128/jb.175.19.6287-6292.1993;
RA   Azakami H., Sugino H., Yokoro N., Iwata N., Murooka Y.;
RT   "moaR, a gene that encodes a positive regulator of the monoamine regulon in
RT   Klebsiella aerogenes.";
RL   J. Bacteriol. 175:6287-6292(1993).
CC   -!- FUNCTION: Positive regulatory protein for the induction of
CC       arylsulfatase synthesis (maoA), tyramine oxidase (tynA), maoC, maoE/F
CC       operon, and atsB/A operon which are all regulated by monoamines, and
CC       included under the common term of monoamine regulon.
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DR   EMBL; D15072; BAA03667.1; -; Genomic_DNA.
DR   RefSeq; WP_002892774.1; NZ_LR134254.1.
DR   AlphaFoldDB; P54794; -.
DR   SMR; P54794; -.
DR   STRING; 548.EAG7_02822; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..227
FT                   /note="Monoamine regulon transcriptional regulator"
FT                   /id="PRO_0000184174"
FT   DOMAIN          155..220
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        179..198
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   227 AA;  26238 MW;  93A92BE2DD168799 CRC64;
     MSALLKASRN DAIIARCLQT ISQLIPLTSA VFYRVNNRLK PENYILHNIS DNTHQQYLEN
     FQPLDPLLPS HFSHQNTTVA AMTPRLCDRN RHYYHEFMLP NNVRDMTEIF IRRERRIVAG
     ISLMRDVPFS SEERQRAQAV LPLVELAIRD CLQEEDDLPA ILTAKEREIV GMVREGASNK
     LIARQLDISL STVKTHLRNI FAKTEVVNRT ELVSRTWMPA AQRTLHL