ID   MOB3A_BOVIN             Reviewed;         217 AA.
AC   Q58D63; Q08E56;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 2.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=MOB kinase activator 3A;
DE   AltName: Full=Mob1 homolog 2A;
DE   AltName: Full=Mps one binder kinase activator-like 2A;
GN   Name=MOB3A; Synonyms=MOBKL2A;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May regulate the activity of kinases. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MOB1/phocein family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAX46581.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; BT021734; AAX46581.1; ALT_FRAME; mRNA.
DR   EMBL; BC123409; AAI23410.1; -; mRNA.
DR   RefSeq; NP_001029401.1; NM_001034229.1.
DR   RefSeq; XP_005209086.1; XM_005209029.3.
DR   RefSeq; XP_005209087.1; XM_005209030.3.
DR   RefSeq; XP_015327590.1; XM_015472104.1.
DR   AlphaFoldDB; Q58D63; -.
DR   SMR; Q58D63; -.
DR   STRING; 9913.ENSBTAP00000019309; -.
DR   PaxDb; Q58D63; -.
DR   PRIDE; Q58D63; -.
DR   Ensembl; ENSBTAT00000019309; ENSBTAP00000019309; ENSBTAG00000014526.
DR   GeneID; 505007; -.
DR   KEGG; bta:505007; -.
DR   CTD; 126308; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014526; -.
DR   VGNC; VGNC:31544; MOB3A.
DR   eggNOG; KOG1903; Eukaryota.
DR   GeneTree; ENSGT01050000244898; -.
DR   HOGENOM; CLU_038321_3_0_1; -.
DR   InParanoid; Q58D63; -.
DR   OMA; AHMGSEA; -.
DR   OrthoDB; 1127941at2759; -.
DR   TreeFam; TF300789; -.
DR   Proteomes; UP000009136; Chromosome 7.
DR   Bgee; ENSBTAG00000014526; Expressed in retropharyngeal lymph node and 105 other tissues.
DR   ExpressionAtlas; Q58D63; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030295; F:protein kinase activator activity; IBA:GO_Central.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   Gene3D; 1.20.140.30; -; 1.
DR   InterPro; IPR005301; MOB_kinase_act_fam.
DR   InterPro; IPR036703; MOB_kinase_act_sf.
DR   PANTHER; PTHR22599; PTHR22599; 1.
DR   Pfam; PF03637; Mob1_phocein; 1.
DR   SMART; SM01388; Mob1_phocein; 1.
DR   SUPFAM; SSF101152; SSF101152; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..217
FT                   /note="MOB kinase activator 3A"
FT                   /id="PRO_0000249710"
FT   BINDING         83
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         88
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         165
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
FT   BINDING         170
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   217 AA;  25410 MW;  6FD0655A8A2CE648 CRC64;
     MSNPFLKQVF NKDKTFRPKR KFEPGTQRFE LHKKAQASLN AGLDLKLAVQ LPAGEELNDW
     VAVHVVDFFN RVNLIYGTIS DGCTERSCPI MSGGPKYEYR WQDENKFRRP TALSAPRYMD
     LLMDWIEVQI NNEDVFPTNV GTPFPKNFLQ VVKKILSRLF RVFVHVYIHH FDRIAQLGSE
     AHVNTCYKHF YYFVTEFGLI DTKELEPLKE MTARMCH