MOB3A_PONAB
ID MOB3A_PONAB Reviewed; 217 AA.
AC Q5R5Z0;
DT 19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=MOB kinase activator 3A;
DE AltName: Full=Mob1 homolog 2A;
DE AltName: Full=Mps one binder kinase activator-like 2A;
GN Name=MOB3A; Synonyms=MOBKL2A;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain cortex;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May regulate the activity of kinases. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOB1/phocein family. {ECO:0000305}.
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DR EMBL; CR860711; CAH92826.1; -; mRNA.
DR RefSeq; NP_001126652.1; NM_001133180.1.
DR AlphaFoldDB; Q5R5Z0; -.
DR SMR; Q5R5Z0; -.
DR STRING; 9601.ENSPPYP00000010478; -.
DR GeneID; 100173650; -.
DR KEGG; pon:100173650; -.
DR CTD; 126308; -.
DR eggNOG; KOG1903; Eukaryota.
DR InParanoid; Q5R5Z0; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.140.30; -; 1.
DR InterPro; IPR005301; MOB_kinase_act_fam.
DR InterPro; IPR036703; MOB_kinase_act_sf.
DR PANTHER; PTHR22599; PTHR22599; 1.
DR Pfam; PF03637; Mob1_phocein; 1.
DR SMART; SM01388; Mob1_phocein; 1.
DR SUPFAM; SSF101152; SSF101152; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..217
FT /note="MOB kinase activator 3A"
FT /id="PRO_0000249711"
FT BINDING 83
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 88
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 165
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 170
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
SQ SEQUENCE 217 AA; 25464 MW; C616C4764456E705 CRC64;
MSNPFLKQVF NKDKTFRPKR KFEPGTQRFE LHKKAQASLN AGLDLRLAVQ LPPGEDLNDW
VTVHVVDFFN RVNLIYGTIS DGCTEQSCPV MSGGPKYEYR WQDEHKFRKP TALSAPRYMD
LLMDWIEAQI NNEDLFPTNV GTPFPKNFLQ AVRKILSRLF RVFVHVYIHH FDRIAQMGSE
AHVNTCYKHF YYFVKEFGLI DTKELEPLKE MTARMCH