MOB3C_BOVIN
ID MOB3C_BOVIN Reviewed; 216 AA.
AC Q5EAA4; A6QQK1;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=MOB kinase activator 3C;
DE AltName: Full=Mob1 homolog 2C;
DE AltName: Full=Mps one binder kinase activator-like 2C;
GN Name=MOB3C; Synonyms=MOBKL2C;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hippocampus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May regulate the activity of kinases. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MOB1/phocein family. {ECO:0000305}.
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DR EMBL; BT020665; AAX08682.1; -; mRNA.
DR EMBL; BC149870; AAI49871.1; -; mRNA.
DR RefSeq; NP_001029927.1; NM_001034755.1.
DR RefSeq; XP_005204908.1; XM_005204851.1.
DR RefSeq; XP_005204909.1; XM_005204852.3.
DR AlphaFoldDB; Q5EAA4; -.
DR SMR; Q5EAA4; -.
DR STRING; 9913.ENSBTAP00000032106; -.
DR PaxDb; Q5EAA4; -.
DR PRIDE; Q5EAA4; -.
DR Ensembl; ENSBTAT00000032168; ENSBTAP00000032106; ENSBTAG00000023551.
DR GeneID; 614275; -.
DR KEGG; bta:614275; -.
DR CTD; 148932; -.
DR VEuPathDB; HostDB:ENSBTAG00000023551; -.
DR VGNC; VGNC:31546; MOB3C.
DR eggNOG; KOG1903; Eukaryota.
DR GeneTree; ENSGT01050000244898; -.
DR HOGENOM; CLU_038321_3_0_1; -.
DR InParanoid; Q5EAA4; -.
DR OMA; QDEHQYR; -.
DR OrthoDB; 1127941at2759; -.
DR TreeFam; TF300789; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000023551; Expressed in ileocecal valve and 101 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030295; F:protein kinase activator activity; IBA:GO_Central.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 1.20.140.30; -; 1.
DR InterPro; IPR005301; MOB_kinase_act_fam.
DR InterPro; IPR036703; MOB_kinase_act_sf.
DR PANTHER; PTHR22599; PTHR22599; 1.
DR Pfam; PF03637; Mob1_phocein; 1.
DR SMART; SM01388; Mob1_phocein; 1.
DR SUPFAM; SSF101152; SSF101152; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..216
FT /note="MOB kinase activator 3C"
FT /id="PRO_0000247548"
FT BINDING 82
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 87
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 164
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
FT BINDING 169
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250"
SQ SEQUENCE 216 AA; 25655 MW; 0E28F8600E23D707 CRC64;
MALCLKQVFS KDKTFRPRKR FEPGTQRFEL YKKAQASLKS GLDLRSVVRL PPGENIDDWI
AVHVVDFFNR INLIYGTMAE RCSETSCPVM AGGPRYEYRW QDERQYRRPA KLSAPRYMAL
LMDWIESLIN DEDVFPTRVG VPFPKNFQQV CTKILTRLFR VFVHVYIHHF DSILSMGAEA
HVNTCYKHFY YFIREFSLVD QRELEPLREM TERICH