ID   MODB_MYCBO              Reviewed;         264 AA.
AC   P0A625; A0A1R3XZJ2; O08061; P95156; X2BJ95;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Molybdenum transport system permease protein ModB;
GN   Name=modB; OrderedLocusNames=BQ2027_MB1889;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system
CC       ModABCD for molybdenum; probably responsible for the translocation of
CC       the substrate across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. CysTW subfamily. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00493.1; -; Genomic_DNA.
DR   RefSeq; NP_855541.1; NC_002945.3.
DR   RefSeq; WP_003409329.1; NC_002945.4.
DR   AlphaFoldDB; P0A625; -.
DR   SMR; P0A625; -.
DR   EnsemblBacteria; SIU00493; SIU00493; BQ2027_MB1889.
DR   GeneID; 45425831; -.
DR   PATRIC; fig|233413.5.peg.2070; -.
DR   OMA; MYSFIET; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015098; F:molybdate ion transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   InterPro; IPR011867; ModB_ABC.
DR   InterPro; IPR006469; NifC_ABC_porter.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR01581; Mo_ABC_porter; 1.
DR   TIGRFAMs; TIGR02141; modB_ABC; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Molybdenum; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..264
FT                   /note="Molybdenum transport system permease protein ModB"
FT                   /id="PRO_0000060115"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          51..253
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   264 AA;  27676 MW;  D20EC44EB28DD526 CRC64;
     MHPPTDLPRW VYLPAIAGIV FVAMPLVAIA IRVDWPRFWA LITTPSSQTA LLLSVKTAAA
     STVLCVLLGV PMALVLARSR GRLVRSLRPL ILLPLVLPPV VGGIALLYAF GRLGLIGRYL
     EAAGISIAFS TAAVVLAQTF VSLPYLVISL EGAARTAGAD YEVVAATLGA RPGTVWWRVT
     LPLLLPGVVS GSVLAFARSL GEFGATLTFA GSRQGVTRTL PLEIYLQRVT DPDAAVALSL
     LLVVVAALVV LGVGARTPIG TDTR