ID   MODD_ECO57              Reviewed;         284 AA.
AC   P58496;
DT   19-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   19-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Putative pyrophosphorylase ModD;
DE            EC=2.4.2.-;
GN   Name=modD; OrderedLocusNames=Z1962, ECs1694;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SIMILARITY: Belongs to the NadC/ModD family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG56050.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB35117.1; -; Genomic_DNA.
DR   PIR; F85698; F85698.
DR   PIR; F90840; F90840.
DR   RefSeq; NP_309721.1; NC_002695.1.
DR   RefSeq; WP_000576838.1; NZ_SDVX01000011.1.
DR   AlphaFoldDB; P58496; -.
DR   SMR; P58496; -.
DR   STRING; 155864.EDL933_1894; -.
DR   EnsemblBacteria; AAG56050; AAG56050; Z1962.
DR   EnsemblBacteria; BAB35117; BAB35117; ECs_1694.
DR   GeneID; 913170; -.
DR   KEGG; ece:Z1962; -.
DR   KEGG; ecs:ECs_1694; -.
DR   PATRIC; fig|386585.9.peg.1793; -.
DR   eggNOG; COG0157; Bacteria.
DR   HOGENOM; CLU_039622_2_1_6; -.
DR   OMA; GGHIHRQ; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   Gene3D; 3.90.1170.20; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006242; ModD.
DR   InterPro; IPR027277; NadC/ModD.
DR   InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR   InterPro; IPR037128; Quinolinate_PRibosylTase_N_sf.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   InterPro; IPR022412; Quinolinate_PRibosylTrfase_N.
DR   PANTHER; PTHR32179; PTHR32179; 1.
DR   Pfam; PF01729; QRPTase_C; 1.
DR   Pfam; PF02749; QRPTase_N; 1.
DR   PIRSF; PIRSF006250; NadC_ModD; 1.
DR   SUPFAM; SSF51690; SSF51690; 1.
DR   TIGRFAMs; TIGR01334; modD; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..284
FT                   /note="Putative pyrophosphorylase ModD"
FT                   /id="PRO_0000155959"
SQ   SEQUENCE   284 AA;  30553 MW;  2A1C04BE799FF909 CRC64;
     MIFLSQAQID ALLLEDIQGG DLTTRALNIG HQHGYIEFFL RQGGCVSGVS VACKMLTTLG
     LTIDDAVSDG SQANAGQRLI RAQGNAAALH QGWKAIQNVL EWSCGVSDYL DQMLALLRER
     YPDGNIACTR KAIPGTRLLA SQAILAAGGL IHRAGCAETI LLFANHRHFL HDNQDWSGAI
     NQLRRHAPEK KIVVEADTPK EAIAALRAQP DVLQLDKFSP QQATEIAQIA PSLAPHCTLA
     LTGGINLTTL KNYLDCGIRL FITSAPYYAA PADIKVSLQP AASI