MOFA1_BOVIN
ID MOFA1_BOVIN Reviewed; 127 AA.
AC Q3ZC61;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=MORF4 family-associated protein 1;
GN Name=MRFAP1 {ECO:0000312|EMBL:AAI02899.1};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1] {ECO:0000312|EMBL:AAI02899.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford {ECO:0000312|EMBL:AAI02899.1};
RC TISSUE=Hypothalamus {ECO:0000312|EMBL:AAI02899.1};
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Found in a complex composed of MORF4L1, MRFAP1 and RB1.
CC Interacts via its N-terminus with MORF4L1. Interacts with CSTB and
CC MORF4L2 (By similarity). {ECO:0000250|UniProtKB:Q5M820,
CC ECO:0000250|UniProtKB:Q9Y605}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y605}.
CC Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9Y605}.
CC Note=Colocalizes with MORF4L1 to cell nuclei.
CC {ECO:0000250|UniProtKB:Q9Y605}.
CC -!- SIMILARITY: Belongs to the MORF4 family-associated protein family.
CC {ECO:0000305}.
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DR EMBL; BC102898; AAI02899.1; -; mRNA.
DR RefSeq; NP_001030421.1; NM_001035344.2.
DR RefSeq; XP_005208399.1; XM_005208342.3.
DR AlphaFoldDB; Q3ZC61; -.
DR SMR; Q3ZC61; -.
DR STRING; 9913.ENSBTAP00000056519; -.
DR PaxDb; Q3ZC61; -.
DR PRIDE; Q3ZC61; -.
DR Ensembl; ENSBTAT00000065893; ENSBTAP00000056519; ENSBTAG00000046936.
DR GeneID; 522338; -.
DR KEGG; bta:522338; -.
DR CTD; 114932; -.
DR VEuPathDB; HostDB:ENSBTAG00000046936; -.
DR eggNOG; ENOG502RU25; Eukaryota.
DR GeneTree; ENSGT00940000155541; -.
DR HOGENOM; CLU_166966_1_0_1; -.
DR InParanoid; Q3ZC61; -.
DR OMA; GRATKRC; -.
DR OrthoDB; 1557272at2759; -.
DR TreeFam; TF338232; -.
DR Proteomes; UP000009136; Chromosome 6.
DR Bgee; ENSBTAG00000046936; Expressed in hypothalamus and 101 other tissues.
DR ExpressionAtlas; Q3ZC61; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR029254; MRFAP1.
DR PANTHER; PTHR31324; PTHR31324; 1.
DR Pfam; PF15155; MRFAP1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..127
FT /note="MORF4 family-associated protein 1"
FT /id="PRO_0000306175"
FT REGION 76..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 92..126
FT /evidence="ECO:0000255"
SQ SEQUENCE 127 AA; 14680 MW; 02176E3FEB732F87 CRC64;
MRPLDIVELA EPEEVEVLEP EEDFEQFLLP VINEMREDIA ALSREHGRAY LRNRSKLWEM
DNMLIQIKTQ VEASEESALN HLQNPDDGAE GRGTKRCEKA EEKAKEIAKM AEMLVELVRR
IEKSESS