ID   MOGR_LISIN              Reviewed;         306 AA.
AC   Q92DX9;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Motility gene repressor MogR;
GN   Name=mogR; OrderedLocusNames=lin0682;
OS   Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=272626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
RN   [2]
RP   FUNCTION.
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=15302931; DOI=10.1073/pnas.0404924101;
RA   Gruendling A., Burrack L.S., Bouwer H.G.A., Higgins D.E.;
RT   "Listeria monocytogenes regulates flagellar motility gene expression
RT   through MogR, a transcriptional repressor required for virulence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:12318-12323(2004).
CC   -!- FUNCTION: Transcriptional repressor of flagellar motility genes, such
CC       as flaA, during extracellular growth at 37 degrees Celsius. Binds
CC       directly to gene promoter region and probably prevents RNA polymerase
CC       binding. At low temperatures, MogR repression activity is modulated by
CC       the DegU response regulator in an unknown mechanism (Probable).
CC       {ECO:0000305|PubMed:15302931}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AL596166; CAC95914.1; -; Genomic_DNA.
DR   PIR; AB1518; AB1518.
DR   RefSeq; WP_010990555.1; NC_003212.1.
DR   AlphaFoldDB; Q92DX9; -.
DR   SMR; Q92DX9; -.
DR   STRING; 272626.lin0682; -.
DR   EnsemblBacteria; CAC95914; CAC95914; CAC95914.
DR   KEGG; lin:lin0682; -.
DR   eggNOG; ENOG50340G0; Bacteria.
DR   HOGENOM; CLU_080650_0_0_9; -.
DR   OMA; VYQFCQR; -.
DR   OrthoDB; 700043at2; -.
DR   Proteomes; UP000002513; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1030; -; 1.
DR   InterPro; IPR021009; MogR_DNA-bd.
DR   InterPro; IPR038245; MogR_DNA-bd_sf.
DR   Pfam; PF12181; MogR_DNAbind; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..306
FT                   /note="Motility gene repressor MogR"
FT                   /id="PRO_0000247904"
SQ   SEQUENCE   306 AA;  35368 MW;  3B3CD1EEDBE218D4 CRC64;
     MPKSEIRKLL QEIKKQVDEP GNSSATEIKK MASEAGINEQ TAEEIYQLLT EFYQAVEEHG
     GIEKYMHSNI SWLKIELELL SACYQIAILE DMKVLDISEM LSLNDLRIFP KTPSQLQNTY
     YKLKKELIQV EDIPKYKPGR KRKTQKNTKK EKTNIFGKVV PAEFKAPTSI KEQISYDKSR
     EKNLVDLLSG VKSNVQLLSE NQGEENNVYD LLKSIYSLSS LAVQKEELDK KYQDLQTKYQ
     ELEQENSYLK QQNETMTDSF HTLVLQVADF AYASDLDQIQ ALPLFSQQLV VTLNQLGVFK
     ENYKQM