MOH1_YEAST
ID MOH1_YEAST Reviewed; 138 AA.
AC P38191; D6VPV0;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Protein yippee-like MOH1;
GN Name=MOH1; OrderedLocusNames=YBL049W; ORFNames=YBL0518;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8154187; DOI=10.1002/yea.320091210;
RA Scherens B., el Bakkoury M., Vierendeels F., Dubois E., Messenguy F.;
RT "Sequencing and functional analysis of a 32,560 bp segment on the left arm
RT of yeast chromosome II. Identification of 26 open reading frames, including
RT the KIP1 and SEC17 genes.";
RL Yeast 9:1355-1371(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7813418; DOI=10.1002/j.1460-2075.1994.tb06923.x;
RA Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C.,
RA Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M.,
RA Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M.,
RA Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H.,
RA Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D.,
RA Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N.,
RA Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J.,
RA Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C.,
RA Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P.,
RA Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y.,
RA Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F.,
RA Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E.,
RA Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M.,
RA Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B.,
RA Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L.,
RA Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M.,
RA Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S.,
RA Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K.,
RA Mewes H.-W., Kleine K.;
RT "Complete DNA sequence of yeast chromosome II.";
RL EMBO J. 13:5795-5809(1994).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
CC -!- SIMILARITY: Belongs to the yippee family. {ECO:0000305}.
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DR EMBL; Z23261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; Z35810; CAA84869.1; -; Genomic_DNA.
DR EMBL; AY692611; AAT92630.1; -; Genomic_DNA.
DR EMBL; BK006936; DAA07070.1; -; Genomic_DNA.
DR PIR; S45784; S45784.
DR RefSeq; NP_009504.1; NM_001178289.1.
DR AlphaFoldDB; P38191; -.
DR BioGRID; 32649; 47.
DR DIP; DIP-2081N; -.
DR IntAct; P38191; 21.
DR STRING; 4932.YBL049W; -.
DR iPTMnet; P38191; -.
DR MaxQB; P38191; -.
DR PaxDb; P38191; -.
DR PRIDE; P38191; -.
DR EnsemblFungi; YBL049W_mRNA; YBL049W; YBL049W.
DR GeneID; 852231; -.
DR KEGG; sce:YBL049W; -.
DR SGD; S000000145; MOH1.
DR VEuPathDB; FungiDB:YBL049W; -.
DR eggNOG; KOG3399; Eukaryota.
DR HOGENOM; CLU_043857_4_1_1; -.
DR InParanoid; P38191; -.
DR OMA; HLAFKGH; -.
DR BioCyc; YEAST:G3O-28948-MON; -.
DR ChiTaRS; MOH1; yeast.
DR PRO; PR:P38191; -.
DR Proteomes; UP000002311; Chromosome II.
DR RNAct; P38191; protein.
DR GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR034751; Yippee.
DR InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR InterPro; IPR039058; Yippee_fam.
DR PANTHER; PTHR13848; PTHR13848; 1.
DR Pfam; PF03226; Yippee-Mis18; 1.
DR PROSITE; PS51792; YIPPEE; 1.
PE 3: Inferred from homology;
KW Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..138
FT /note="Protein yippee-like MOH1"
FT /id="PRO_0000212410"
FT DOMAIN 41..138
FT /note="Yippee"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 45
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 48
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 101
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 104
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
SQ SEQUENCE 138 AA; 16085 MW; C76DE1D470042D90 CRC64;
MGLRYSIYIE NPLSSPSSSY KSINDPLFHS QHRSQKNVSF ITYGCRHCKT HLSSSFQIIS
RDYRGRTGTA YLMNKVVNVV EGKVEQRRML TGDYLVCDIL CHWCKRNVGW KYLQSSNDDQ
QYKEGKFILE LKNICKCT
