MON1A_CHICK
ID MON1A_CHICK Reviewed; 549 AA.
AC Q5ZIH2;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Vacuolar fusion protein MON1 homolog A;
GN Name=MON1A; ORFNames=RCJMB04_26e14;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Plays an important role in membrane trafficking through the
CC secretory apparatus. Not involved in endocytic trafficking to
CC lysosomes. {ECO:0000250|UniProtKB:Q6PDG8}.
CC -!- SIMILARITY: Belongs to the MON1/SAND family. {ECO:0000305}.
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DR EMBL; AJ720812; CAG32471.1; -; mRNA.
DR RefSeq; NP_001025758.1; NM_001030587.2.
DR AlphaFoldDB; Q5ZIH2; -.
DR SMR; Q5ZIH2; -.
DR STRING; 9031.ENSGALP00000004599; -.
DR PaxDb; Q5ZIH2; -.
DR GeneID; 415929; -.
DR KEGG; gga:415929; -.
DR CTD; 84315; -.
DR VEuPathDB; HostDB:geneid_415929; -.
DR eggNOG; KOG0997; Eukaryota.
DR InParanoid; Q5ZIH2; -.
DR OrthoDB; 829786at2759; -.
DR PhylomeDB; Q5ZIH2; -.
DR PRO; PR:Q5ZIH2; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR InterPro; IPR043970; FUZ/MON1/HPS1_longin_3.
DR InterPro; IPR004353; Mon1.
DR PANTHER; PTHR13027; PTHR13027; 1.
DR Pfam; PF19036; Fuz_longin_1; 1.
DR Pfam; PF19037; Fuz_longin_2; 1.
DR Pfam; PF19038; Fuz_longin_3; 1.
DR PRINTS; PR01546; YEAST73DUF.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..549
FT /note="Vacuolar fusion protein MON1 homolog A"
FT /id="PRO_0000285764"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 62049 MW; 0A837EFBCBB17117 CRC64;
MAADVHKKKG WEVPNGSLAP GDGQHAERSE SPTPGLAQGT EPGAGQEGAM FVHTRSYEDL
TSPEDGGAVV RSPEERRGEP AEPTSMEQIS KDFSELSTQL TGMALDLEEE MRQSQEGKLE
PSPQATRHDS VLSGKEEEDV TMDTWRMHRK HVFVLSEAGK PVYSRYGSEE ALSSTMGVMM
ALVSFLEAEK NAIRSIHADG YKVVFVRRSP LVLVAVARTR QSEQEIAHEL LYIYYQILSL
LTWTQLNHIF QQKQNYDLRR LLAGSERITD NLLDLMAHDP SFLMGAVRCL PLAASVRDAV
STSLQQAKAK SLVFSILLSG NQLVSLVRKK DQFLHPIDLH LLFNLISSSS SFREGEAWTP
ICLPKFNSSG FFHAHISYLE QEMDLCLLLV STDREDFFTV SDCKRRFQER LRRRGVHHAL
QEALRTPFYS VAQVGIPDLR HFIYKSKSSG LFTSPEIEAP YVREEEKERL LGLYQYLHSR
AHNSSCPLKN IYFTGPRENL LAWVTSAFEL YICYSPLGTK AGAISAVNKL MKWIRKEEDR
LFILTPQTY