ID   MON1_ASPOR              Reviewed;         628 AA.
AC   Q2ULR1;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Vacuolar fusion protein mon1;
GN   Name=mon1; ORFNames=AO090003000303;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Required for multiple vacuole delivery pathways including the
CC       cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and
CC       endocytosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endosome, multivesicular body membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Prevacuolar
CC       compartment membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}. Vacuole membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MON1/SAND family. {ECO:0000305}.
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DR   EMBL; AP007155; BAE57504.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2ULR1; -.
DR   SMR; Q2ULR1; -.
DR   STRING; 510516.Q2ULR1; -.
DR   EnsemblFungi; BAE57504; BAE57504; AO090003000303.
DR   HOGENOM; CLU_014574_5_0_1; -.
DR   OMA; TNSTCEY; -.
DR   Proteomes; UP000006564; Chromosome 2.
DR   GO; GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR   InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR   InterPro; IPR043970; FUZ/MON1/HPS1_longin_3.
DR   InterPro; IPR004353; Mon1.
DR   PANTHER; PTHR13027; PTHR13027; 1.
DR   Pfam; PF19036; Fuz_longin_1; 1.
DR   Pfam; PF19037; Fuz_longin_2; 1.
DR   Pfam; PF19038; Fuz_longin_3; 1.
DR   PRINTS; PR01546; YEAST73DUF.
PE   3: Inferred from homology;
KW   Autophagy; Endosome; Membrane; Protein transport; Reference proteome;
KW   Transport; Vacuole.
FT   CHAIN           1..628
FT                   /note="Vacuolar fusion protein mon1"
FT                   /id="PRO_0000278854"
FT   REGION          1..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..43
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..141
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   628 AA;  68843 MW;  568B34D7992A9D44 CRC64;
     MDSEIKNQLQ DSLGGNDDSK DDITCSSKSS PTMAASSVRE RSTSPEGPPP PLPPRPNTLN
     LLDEGASSSR TLRQSTQSAL QSRATTAVSL TDIASHDGGK ESYPARGLPG TLRAKASLSH
     LASPRGSDTA DSASVKSSVP QTDFGEVENV FSDFVATESG PMQHDSTGLL QFPEFQADDV
     DDDFTEEFEP VGDVGDEGEN EVLENWKSKR KHYLILSAAG KPIWTRHGDG GLISTYIGVI
     QTIISFYEDS QDRLNSFTAG DTKFVIVAKG PLYLVAISRI LESETQLKLQ LEALYMQILS
     TLTLPSLTHL FSVRPSTDLK RPLQGSETLL STLADSFTKG SPSTLLSALE CLKIRKAHRQ
     TINNALLKTR TNSLLYGLVV AGGRLVSVVR PRKHSLHPGD LQLIFNMVFE AEAVKAGGGE
     SWIPVCLPGF NSSGYLYMYV SFVDLREDAG NVADDTATKE ESVAVILIST DKERFFELQE
     MRNSFIEQLE KDGSLKIMKE AIDKGRPKTT DIVPGTVLHH FLYKSRGNVQ FTMSSYEPDF
     SSVSRRRRLM STYNNLHASI HSKHAHVRVH HCVSQSSTSL AWVTPVFQLY CVAGPNANRN
     ALAHSASKIV QWVQQEEERL FIIGGAVF