ID   MON1_ASPTN              Reviewed;         556 AA.
AC   Q0CJY1;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Vacuolar fusion protein mon1;
GN   Name=mon1; ORFNames=ATEG_06003;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for multiple vacuole delivery pathways including the
CC       cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and
CC       endocytosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endosome, multivesicular body membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Prevacuolar
CC       compartment membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}. Vacuole membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MON1/SAND family. {ECO:0000305}.
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DR   EMBL; CH476601; EAU33764.1; -; Genomic_DNA.
DR   RefSeq; XP_001215181.1; XM_001215181.1.
DR   AlphaFoldDB; Q0CJY1; -.
DR   SMR; Q0CJY1; -.
DR   STRING; 341663.Q0CJY1; -.
DR   EnsemblFungi; EAU33764; EAU33764; ATEG_06003.
DR   GeneID; 4321578; -.
DR   VEuPathDB; FungiDB:ATEG_06003; -.
DR   eggNOG; KOG0997; Eukaryota.
DR   HOGENOM; CLU_014574_5_0_1; -.
DR   OMA; TLHEMRD; -.
DR   OrthoDB; 829786at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR   InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR   InterPro; IPR004353; Mon1.
DR   PANTHER; PTHR13027; PTHR13027; 1.
DR   Pfam; PF19036; Fuz_longin_1; 1.
DR   Pfam; PF19037; Fuz_longin_2; 1.
DR   PRINTS; PR01546; YEAST73DUF.
PE   3: Inferred from homology;
KW   Autophagy; Endosome; Membrane; Protein transport; Reference proteome;
KW   Transport; Vacuole.
FT   CHAIN           1..556
FT                   /note="Vacuolar fusion protein mon1"
FT                   /id="PRO_0000278855"
FT   REGION          1..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   556 AA;  60771 MW;  106EE3CD811B694F CRC64;
     MDLTDQSRPQ TASGDDPDGR VENAPSSSTT TASVGTNDRT ETANPEEQPP PLPPRPNTLS
     LLDEGGASSR SLRQTGPVNL QSKATTAVTI PDIASNDAGK ENYNLRGLAG ALRAKASLSH
     LASSRASEAG DSASVRSSVP HTEAGEMENV FGDLLAAESG VVQQDGTGLL QFPEFQADDV
     EDDFACEFEP VGEVEEGEDN EEMVLEKWKS KRKHYLILSA AGKPIWTRHG DGALISTYVG
     IIQTIISFFQ DSDDHLRSFT AGDTKFVVVT KGPLYFVAIS RIHESETQLK LQLEALYMQI
     LSTLTLPSLT HLFSVRPSTD LKRPLQGSET LLSTLADSFT RGSPSTLLSA LECLKIRKAH
     RHIINNTLLK SRVNSLLYGL VVAGGRLVSV VRPKKHSLHP GDLQLLFSMI FEAEAVKTGG
     GESWIPVCLP GFNSSGYLYM YVSFLDLRED SSNVADDSTT KEESVAIVLI STDKESFFEL
     QEMRNNLVEQ LQKNYSLQVI KEAIDRGRPA TTDIVPGTVL HHFLYKSRAN VQFTMSSYDP
     EFSSISRRRR SVSLSS