ID   MON1_PHANO              Reviewed;         722 AA.
AC   Q0U822;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Vacuolar fusion protein MON1;
GN   Name=MON1; ORFNames=SNOG_12092;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: Required for multiple vacuole delivery pathways including the
CC       cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and
CC       endocytosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endosome, multivesicular body membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Prevacuolar
CC       compartment membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}. Vacuole membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MON1/SAND family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAT80504.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH445345; EAT80504.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001802326.1; XM_001802274.1.
DR   AlphaFoldDB; Q0U822; -.
DR   SMR; Q0U822; -.
DR   STRING; 13684.SNOT_12092; -.
DR   PRIDE; Q0U822; -.
DR   GeneID; 5979236; -.
DR   KEGG; pno:SNOG_12092; -.
DR   eggNOG; KOG0997; Eukaryota.
DR   InParanoid; Q0U822; -.
DR   OMA; INTACMA; -.
DR   OrthoDB; 829786at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IBA:GO_Central.
DR   GO; GO:0035658; C:Mon1-Ccz1 complex; IBA:GO_Central.
DR   GO; GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR   InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR   InterPro; IPR043970; FUZ/MON1/HPS1_longin_3.
DR   InterPro; IPR004353; Mon1.
DR   PANTHER; PTHR13027; PTHR13027; 1.
DR   Pfam; PF19036; Fuz_longin_1; 1.
DR   Pfam; PF19037; Fuz_longin_2; 1.
DR   Pfam; PF19038; Fuz_longin_3; 1.
DR   PRINTS; PR01546; YEAST73DUF.
PE   3: Inferred from homology;
KW   Autophagy; Endosome; Membrane; Protein transport; Reference proteome;
KW   Transport; Vacuole.
FT   CHAIN           1..722
FT                   /note="Vacuolar fusion protein MON1"
FT                   /id="PRO_0000278865"
FT   REGION          1..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..58
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   722 AA;  79921 MW;  8651621A24656656 CRC64;
     MAPLRGPTRA STSGISSQSR EGTPPPLPPR PQLGNLPSRP STSYSIRKAP SRPQLVSKAT
     TQLSLSTGQA FGTESRDDAA SIATKQRSFL GANLHSHSTS DADDSASIRS YMPGTEGVGE
     GESILGEVLG HEQKTDTEKT LLRSLGHKFG DGEAQSMFPP DPQFDAAFNR EFDEVDEMSV
     DGSNEEAVMR QWRAKLKHFL ILSSAGKPIY SRHGDDQLIT NYIGVVQTII SFYQSTNDVL
     RGFTAGDVRF VVMSKGPLNL VAITRLPESD SQLRTQLEAL YMQILSTLTL PSLERMFAAR
     ANYDLRRPLQ GTDTLLSALA DGFTRGSSST LLSALECLKL RKSHRTTINN TLLKTRSENL
     LYGLIVASGK LVSVVRPKKH SLHPGDLHLI FNMLFEAGSV KAGGGENWIP LCLPGFNNTG
     YLYMYVSFLN LEHPTEQMQE RPSTSEGAPD EVAILLISAE KESFFELRSM RDDLVETLQR
     NGSIEAMRAA VRQGRPKCTD IVPGSPLRHF LYKSRGNVQF TMPSFEPYFE NALDKRRLLN
     LYNKLHSNVH NKPTTLKVHH ETGTSCIALA WSTPLFELYA VAPAATSRAA LAQSANKIIQ
     TKLPSREKMN SFYGTLRLLS REFAPCPLPR SSHTESCKWQ LNVRHIHANQ YLSNWNAAGA
     QTFSHQSPTQ SPWVCIDWIG RYLDEARSKV TQSATMPSGP LGRRVISPDE VRLYPHSCVQ
     EA