ID   MOR2_SCHPO              Reviewed;        2196 AA.
AC   Q9HDV6;
DT   06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Cell polarity protein mor2;
DE   AltName: Full=Morphological round protein 2;
GN   Name=mor2; ORFNames=SPBP19A11.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND SUBCELLULAR LOCATION.
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=12234926; DOI=10.1093/emboj/cdf495;
RA   Hirata D., Kishimoto N., Suda M., Sogabe Y., Nakagawa S., Yoshida Y.,
RA   Sakai K., Mizunuma M., Miyakawa T., Ishiguro J., Toda T.;
RT   "Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is
RT   essential for cell morphogenesis and its mutation induces Wee1-dependent G2
RT   delay.";
RL   EMBO J. 21:4863-4874(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Required for the maintenance of cell polarity. Has a role in
CC       localizing F-actin at the cell tips. {ECO:0000269|PubMed:12234926}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12234926}. Membrane
CC       {ECO:0000269|PubMed:12234926}; Peripheral membrane protein
CC       {ECO:0000269|PubMed:12234926}. Note=Found at the cell tips and at the
CC       site of septum formation.
CC   -!- SIMILARITY: To yeast TAO3/PAG1. {ECO:0000305}.
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DR   EMBL; AB093007; BAC20935.1; -; Genomic_DNA.
DR   EMBL; CU329671; CAC19754.1; -; Genomic_DNA.
DR   RefSeq; NP_596172.1; NM_001022092.2.
DR   AlphaFoldDB; Q9HDV6; -.
DR   SMR; Q9HDV6; -.
DR   BioGRID; 277829; 12.
DR   STRING; 4896.SPBP19A11.04c.1; -.
DR   iPTMnet; Q9HDV6; -.
DR   MaxQB; Q9HDV6; -.
DR   PaxDb; Q9HDV6; -.
DR   PRIDE; Q9HDV6; -.
DR   EnsemblFungi; SPBP19A11.04c.1; SPBP19A11.04c.1:pep; SPBP19A11.04c.
DR   GeneID; 2541317; -.
DR   KEGG; spo:SPBP19A11.04c; -.
DR   PomBase; SPBP19A11.04c; mor2.
DR   VEuPathDB; FungiDB:SPBP19A11.04c; -.
DR   eggNOG; KOG1825; Eukaryota.
DR   HOGENOM; CLU_000325_1_0_1; -.
DR   InParanoid; Q9HDV6; -.
DR   OMA; HAQQVTI; -.
DR   PhylomeDB; Q9HDV6; -.
DR   PRO; PR:Q9HDV6; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005938; C:cell cortex; IBA:GO_Central.
DR   GO; GO:0051285; C:cell cortex of cell tip; IDA:PomBase.
DR   GO; GO:1902716; C:cell cortex of growing cell tip; IDA:PomBase.
DR   GO; GO:0032153; C:cell division site; IDA:PomBase.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR   GO; GO:0031097; C:medial cortex; IDA:PomBase.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030427; C:site of polarized growth; IBA:GO_Central.
DR   GO; GO:0000902; P:cell morphogenesis; IBA:GO_Central.
DR   GO; GO:0062200; P:RAM/MOR signaling pathway; IMP:PomBase.
DR   GO; GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR025614; Cell_morpho_N.
DR   InterPro; IPR025481; Cell_Morphogen_C.
DR   InterPro; IPR039867; Furry/Tao3/Mor2.
DR   InterPro; IPR029473; MOR2-PAG1_mid.
DR   PANTHER; PTHR12295; PTHR12295; 1.
DR   Pfam; PF14225; MOR2-PAG1_C; 1.
DR   Pfam; PF14228; MOR2-PAG1_mid; 3.
DR   Pfam; PF14222; MOR2-PAG1_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   4: Predicted;
KW   Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..2196
FT                   /note="Cell polarity protein mor2"
FT                   /id="PRO_0000096536"
SQ   SEQUENCE   2196 AA;  251198 MW;  AAF2698DB00DE4CF CRC64;
     MSLNEIAHDQ PVENGPLYSE KQDHTAVDYA LHILFTQFVR LSEQKISFLS RYHANEGKNA
     EPVRFNVGEQ EAILLLKKGE DNEFDRCIQA LVALASSKPV AVIESLLCWR KVRVDITSSS
     GTPRVVNERR SSISIYILCR VLTEIAETIP SNALEESTVS CLLECVFHQL LSAKNLPVSS
     SYFSLANWES FAFLVGSMSR FNFVMVSDRF IEEIEHLEKS GCDSRQKETV LVHLLRAMRY
     LRLQLYPTTL LEESIAFLQS LTSFFMKANT ALKIEYAYLM EQLLRPLISR ATFEVNIPAW
     SRTIETIYPV VLKMCTKTKY WNVFFPFCCT LLCLSPKQFF LKHWISSLDA AFFRVKDRRL
     RNTGLPHLSR VVWTYSNQYK EEPSIMNSNI SNILKSGFSI GKKFSVVPFA TLEELDGYAQ
     IVRVVGAHFP ELVIKEILTP LSTDAFTENI GPEKLMIVVR SVYYILHDMK YKKSDSTIFE
     YIEFEFVDLH EVAVGTPLQQ FVHNLSQKLL FLVFQLSTNT NCYLDSKNAT SLLALYINAL
     KVFPCLMGKL EQRVIDAYVK CLNCSNKIIH TVCHNSLIYF SSGLKMSKSV ISCLSRKLVK
     GSEYLLRTYH EVIRIWISQQ EAVIEKRNSV LSNKSCASSE SNTPASVKQD YDDIQSWTII
     EEIQSLGVLH LSSPSVGIRK FAVALLNDVK QLNTEYLMLS SDKVEVGDIY SEPTIVDVLK
     DCDSSILSVE SHLPTAAERS RLRKFINDGT KDMLLKLATS NSGVDISIWY NVFPRFIKVC
     FERFPTTMAL LRNTVCEKLP SITMQLLSRI ESSELNFNLK SAVKNDNFPE FLLVQWKLYL
     IVACCTITYT SNVDYSHTDL RRTLTAVQSG NHLRGLQETI KITSAESLFS MVLPLIFTEF
     SPIREAVVFA IGCINVNAFP QLVRSLKPYI SVLKQDHQEF IFAGLNFPSV KRRNKPDLLL
     RSEIAHIFAM TSHLLLHELL NEDREALSVI SEFLKDLKGF LSTPNVQADE KYLKLRCYFS
     QLLEKVLLVQ NLHPSSEVLP FSGRASCWKL LDEWTGFGPA RAITKNREEL MRAHIRGNNK
     DIRERDKLLA SFEAGKQNLE YLAIKAMIAL CTAKLQQELT EGVFLFDIEI LLNWFTAVFG
     SPSKAIVGLA RKGLTALLLE NSSNEVLLQK VINRCFSKEI SQTISNYYFL SLSEMLIQIN
     PNNLSKPKLL PLCLVNLSTN NLSVRLKAFE LLGNFHLNNF TMTALMEFKT FLESSNPALY
     LKPQYLFSVQ LASDFTEDSF TLTSECLRYF NYGHQHRRGL VTVLLPWLQN LELKMDVENK
     TFDSFTAVIL IDLIEVTAKF TNDLPNEIEA LWTSLALSRH KSNWTVILFF LMQQCYQRKT
     FSFVDCTRQI TIYLAKTELL SDLYSTLLSF VCPANVSNEN QEVYKFSLED LSSTYVANLE
     DLFPSEKNHI SYSPCQLSLL LLMDILPNPS IITVTDDVAT ILHAAFIQFD HYSRIVQEQC
     QQIFQYVVRK VLAMEGRLDY DDAYFDFNVE SSLITGLRGK TKKEDDLVKY HNMILKTIEL
     LSSSYPELKQ IWGEVALSWA TTCPSRRLAC NSFQLFRSLL PDFDARMLLE IISRLVGTIS
     DETSYLRDYS VEILRTFNSY VLVMNSDDLL SYSQILWTAI ACLTTIHEDE FIESVKIAYA
     YFLRVEETDS ATQQIMETFP QNWVGDYQGL QILILKGFRS TNSFEITMNF FLLLMDFKDN
     DLVGVGYLRI LSCLLVSLPA MVYTYEHSDP ITFDLSVFCH KLATLASQFN DDALIELLDT
     YLKRKFRSIK DFLKHTVSYL YSYYFEDYEL EIVSTLTMFL SNNLTWFRKS TLDVLKELFP
     LIDFQKPIYS EHGLGIVSPL LRLLPTGYAM EALSLLTDSV LHVSAPTDMQ TLKLLMVDPK
     LKNSDDRLAG FFEIPDEDGW YEPNSEYAAA ITKSNVHAVF YSCSTTEASV STPEVRFHAD
     EVSNYPRHVP TDSHGSLDEN SLGELVTTLH SLDVFFAEDR DEELIQPDVA VDPKLDITSE
     DYDDRIATIL SGSLRRQKQG LMAYETESFR DYSPNEEIDA SAKLPMDMPP VRVRKSSFIS
     KLKPHYFMDA ESYYPSLKAL GNSAEHRLSL DEIRGAAELK QNKNWNSMLD QSVSMINEDS
     VEDHETHENY YHLRTMFQGS ESNESFTDTT RSRGWH