MORN3_MOUSE
ID MORN3_MOUSE Reviewed; 241 AA.
AC Q8C5T4; Q8VE21; Q9D5H6;
DT 25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2006, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=MORN repeat-containing protein 3;
GN Name=Morn3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8C5T4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8C5T4-2; Sequence=VSP_019998, VSP_019999;
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DR EMBL; AK015339; BAB29804.1; -; mRNA.
DR EMBL; AK077141; BAC36639.1; -; mRNA.
DR EMBL; BC019987; AAH19987.1; -; mRNA.
DR CCDS; CCDS19659.1; -. [Q8C5T4-1]
DR CCDS; CCDS84956.1; -. [Q8C5T4-2]
DR RefSeq; NP_001334385.1; NM_001347456.1. [Q8C5T4-2]
DR RefSeq; NP_083388.1; NM_029112.1. [Q8C5T4-1]
DR RefSeq; XP_006530538.1; XM_006530475.3. [Q8C5T4-1]
DR RefSeq; XP_006530539.1; XM_006530476.3. [Q8C5T4-1]
DR RefSeq; XP_006530541.1; XM_006530478.3. [Q8C5T4-2]
DR RefSeq; XP_011246546.1; XM_011248244.2. [Q8C5T4-1]
DR AlphaFoldDB; Q8C5T4; -.
DR SMR; Q8C5T4; -.
DR STRING; 10090.ENSMUSP00000031437; -.
DR iPTMnet; Q8C5T4; -.
DR PhosphoSitePlus; Q8C5T4; -.
DR PaxDb; Q8C5T4; -.
DR PRIDE; Q8C5T4; -.
DR ProteomicsDB; 290277; -. [Q8C5T4-1]
DR ProteomicsDB; 290278; -. [Q8C5T4-2]
DR Antibodypedia; 64782; 94 antibodies from 16 providers.
DR DNASU; 74890; -.
DR Ensembl; ENSMUST00000031437; ENSMUSP00000031437; ENSMUSG00000029477. [Q8C5T4-1]
DR Ensembl; ENSMUST00000045843; ENSMUSP00000041714; ENSMUSG00000029477. [Q8C5T4-2]
DR Ensembl; ENSMUST00000132775; ENSMUSP00000120199; ENSMUSG00000029477. [Q8C5T4-2]
DR GeneID; 74890; -.
DR KEGG; mmu:74890; -.
DR UCSC; uc008zna.1; mouse. [Q8C5T4-1]
DR UCSC; uc008znb.1; mouse. [Q8C5T4-2]
DR CTD; 283385; -.
DR MGI; MGI:1922140; Morn3.
DR VEuPathDB; HostDB:ENSMUSG00000029477; -.
DR eggNOG; KOG0231; Eukaryota.
DR GeneTree; ENSGT00940000159285; -.
DR HOGENOM; CLU_032017_5_2_1; -.
DR InParanoid; Q8C5T4; -.
DR OMA; GEGKQYY; -.
DR OrthoDB; 1309439at2759; -.
DR PhylomeDB; Q8C5T4; -.
DR TreeFam; TF323893; -.
DR BioGRID-ORCS; 74890; 1 hit in 70 CRISPR screens.
DR ChiTaRS; Morn3; mouse.
DR PRO; PR:Q8C5T4; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q8C5T4; protein.
DR Bgee; ENSMUSG00000029477; Expressed in seminiferous tubule of testis and 56 other tissues.
DR ExpressionAtlas; Q8C5T4; baseline and differential.
DR Genevisible; Q8C5T4; MM.
DR InterPro; IPR003409; MORN.
DR Pfam; PF02493; MORN; 5.
DR SMART; SM00698; MORN; 6.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome; Repeat.
FT CHAIN 1..241
FT /note="MORN repeat-containing protein 3"
FT /id="PRO_0000247461"
FT REPEAT 38..60
FT /note="MORN 1"
FT REPEAT 62..84
FT /note="MORN 2"
FT REPEAT 91..113
FT /note="MORN 3"
FT REPEAT 114..136
FT /note="MORN 4"
FT REPEAT 137..159
FT /note="MORN 5"
FT REPEAT 160..182
FT /note="MORN 6"
FT REPEAT 184..205
FT /note="MORN 7"
FT VAR_SEQ 155..169
FT /note="KNGNRYEGIWERGMK -> SGDSRPRWCAEGSVG (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_019998"
FT VAR_SEQ 170..241
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_019999"
FT CONFLICT 86
FT /note="K -> I (in Ref. 1; BAB29804)"
FT /evidence="ECO:0000305"
FT CONFLICT 97
FT /note="G -> D (in Ref. 1; BAB29804)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 241 AA; 27881 MW; 40344D7931550B0E CRC64;
MPVTKCPRKV EPPWKGWDRK AQKNGLRHQV FAVNGDHYVG EWKGNLKHGK GTQVWKKSGA
VYEGDWKFGK RDGYGSLSHP DPETGKLRRV YSGWWKGDKK SGYGIQFFGP KEYYEGEWCN
NQRSGWGRMY YNNGDIYEGQ WQNDKPEGEG MLRLKNGNRY EGIWERGMKN GHGRFFHLDH
GQLFEGYWVD NVAKCGTMID FGRDEAPEPT QFPIPKVEIL DPDGVLKEAL DKLMKPEEEE
G
