位置:首页 > 蛋白库 > MORN4_PONAB
MORN4_PONAB
ID   MORN4_PONAB             Reviewed;         146 AA.
AC   Q5R578;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=MORN repeat-containing protein 4;
GN   Name=MORN4;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in promoting axonal degeneration following
CC       neuronal injury by toxic insult or trauma.
CC       {ECO:0000250|UniProtKB:Q6PGF2}.
CC   -!- SUBUNIT: Interacts with MYO3A. {ECO:0000250|UniProtKB:Q8NDC4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8NDC4}. Cell
CC       projection, filopodium tip {ECO:0000250|UniProtKB:Q8NDC4}. Cell
CC       projection, stereocilium {ECO:0000250|UniProtKB:Q6PGF2}. Note=Found in
CC       the cytoplasm in the absence of MYO3A and localizes at filopodial tips
CC       in the presence of MYO3A. {ECO:0000250|UniProtKB:Q8NDC4}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR860986; CAH93088.1; -; mRNA.
DR   RefSeq; NP_001126828.1; NM_001133356.1.
DR   AlphaFoldDB; Q5R578; -.
DR   SMR; Q5R578; -.
DR   STRING; 9601.ENSPPYP00000002945; -.
DR   Ensembl; ENSPPYT00000043703; ENSPPYP00000028389; ENSPPYG00000031901.
DR   GeneID; 100173834; -.
DR   KEGG; pon:100173834; -.
DR   CTD; 118812; -.
DR   eggNOG; KOG0231; Eukaryota.
DR   GeneTree; ENSGT00730000111173; -.
DR   HOGENOM; CLU_113346_0_0_1; -.
DR   InParanoid; Q5R578; -.
DR   OMA; WFPDGAK; -.
DR   OrthoDB; 1532474at2759; -.
DR   TreeFam; TF323893; -.
DR   Proteomes; UP000001595; Chromosome 10.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0032433; C:filopodium tip; ISS:UniProtKB.
DR   GO; GO:0032426; C:stereocilium tip; ISS:UniProtKB.
DR   GO; GO:0048678; P:response to axon injury; ISS:UniProtKB.
DR   InterPro; IPR003409; MORN.
DR   Pfam; PF02493; MORN; 4.
DR   SMART; SM00698; MORN; 4.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Reference proteome; Repeat.
FT   CHAIN           1..146
FT                   /note="MORN repeat-containing protein 4"
FT                   /id="PRO_0000279490"
FT   REPEAT          16..38
FT                   /note="MORN 1"
FT   REPEAT          39..61
FT                   /note="MORN 2"
FT   REPEAT          62..84
FT                   /note="MORN 3"
FT   REPEAT          85..107
FT                   /note="MORN 4"
SQ   SEQUENCE   146 AA;  16236 MW;  4DCF6DAD95100D1C CRC64;
     MTLTKGSFTY SSGEEYRGEW KEGRRHGFGQ LMFADGGTYL GHFENGLFNG FGVLTFSDGS
     RYEGEFAQGK FNGVGVFIRY DNMTFEGEFK NGRVDGFGLL TFPDGSHGIP RNEGLFENNK
     LLRREKCSAI VQRAQSASKS ARNLTA
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024