MORN4_RAT
ID MORN4_RAT Reviewed; 146 AA.
AC Q5BJS9;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=MORN repeat-containing protein 4;
GN Name=Morn4;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Plays a role in promoting axonal degeneration following
CC neuronal injury by toxic insult or trauma.
CC {ECO:0000250|UniProtKB:Q6PGF2}.
CC -!- SUBUNIT: Interacts with MYO3A. {ECO:0000250|UniProtKB:Q8NDC4}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8NDC4}. Cell
CC projection, filopodium tip {ECO:0000250|UniProtKB:Q8NDC4}. Cell
CC projection, stereocilium {ECO:0000250|UniProtKB:Q6PGF2}. Note=Found in
CC the cytoplasm in the absence of MYO3A and localizes at filopodial tips
CC in the presence of MYO3A. {ECO:0000250|UniProtKB:Q8NDC4}.
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DR EMBL; BC091345; AAH91345.1; -; mRNA.
DR RefSeq; NP_001020146.1; NM_001024975.1.
DR AlphaFoldDB; Q5BJS9; -.
DR SMR; Q5BJS9; -.
DR STRING; 10116.ENSRNOP00000032408; -.
DR PaxDb; Q5BJS9; -.
DR PRIDE; Q5BJS9; -.
DR Ensembl; ENSRNOT00000037490; ENSRNOP00000032408; ENSRNOG00000027156.
DR GeneID; 293950; -.
DR KEGG; rno:293950; -.
DR UCSC; RGD:1307336; rat.
DR CTD; 118812; -.
DR RGD; 1307336; Morn4.
DR eggNOG; KOG0231; Eukaryota.
DR GeneTree; ENSGT00730000111173; -.
DR HOGENOM; CLU_113346_0_0_1; -.
DR InParanoid; Q5BJS9; -.
DR OMA; WFPDGAK; -.
DR OrthoDB; 1532474at2759; -.
DR PhylomeDB; Q5BJS9; -.
DR TreeFam; TF323893; -.
DR PRO; PR:Q5BJS9; -.
DR Proteomes; UP000002494; Chromosome 1.
DR Bgee; ENSRNOG00000027156; Expressed in testis and 19 other tissues.
DR ExpressionAtlas; Q5BJS9; baseline and differential.
DR Genevisible; Q5BJS9; RN.
DR GO; GO:0042995; C:cell projection; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0032433; C:filopodium tip; ISS:UniProtKB.
DR GO; GO:0032426; C:stereocilium tip; ISS:UniProtKB.
DR GO; GO:0048678; P:response to axon injury; ISS:UniProtKB.
DR InterPro; IPR003409; MORN.
DR Pfam; PF02493; MORN; 4.
DR SMART; SM00698; MORN; 4.
PE 2: Evidence at transcript level;
KW Cell projection; Cytoplasm; Reference proteome; Repeat.
FT CHAIN 1..146
FT /note="MORN repeat-containing protein 4"
FT /id="PRO_0000279491"
FT REPEAT 16..38
FT /note="MORN 1"
FT REPEAT 39..61
FT /note="MORN 2"
FT REPEAT 62..84
FT /note="MORN 3"
FT REPEAT 85..107
FT /note="MORN 4"
SQ SEQUENCE 146 AA; 16238 MW; A54243B274F70A7A CRC64;
MTLTKGSFTY SSGEEYRGEW KEGRRHGFGQ LMFADGGTYL GHFENGLFNG FGVLTFSDGS
RYEGEFSQGK FNGVGVFIRY DNMTFEGEFK NGRVDGFGLL TFPDGSHGLP RNEGLFENNK
LLRREKCSAV VQRAQSASKS ARNLTA