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MORN4_RAT
ID   MORN4_RAT               Reviewed;         146 AA.
AC   Q5BJS9;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=MORN repeat-containing protein 4;
GN   Name=Morn4;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Plays a role in promoting axonal degeneration following
CC       neuronal injury by toxic insult or trauma.
CC       {ECO:0000250|UniProtKB:Q6PGF2}.
CC   -!- SUBUNIT: Interacts with MYO3A. {ECO:0000250|UniProtKB:Q8NDC4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q8NDC4}. Cell
CC       projection, filopodium tip {ECO:0000250|UniProtKB:Q8NDC4}. Cell
CC       projection, stereocilium {ECO:0000250|UniProtKB:Q6PGF2}. Note=Found in
CC       the cytoplasm in the absence of MYO3A and localizes at filopodial tips
CC       in the presence of MYO3A. {ECO:0000250|UniProtKB:Q8NDC4}.
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DR   EMBL; BC091345; AAH91345.1; -; mRNA.
DR   RefSeq; NP_001020146.1; NM_001024975.1.
DR   AlphaFoldDB; Q5BJS9; -.
DR   SMR; Q5BJS9; -.
DR   STRING; 10116.ENSRNOP00000032408; -.
DR   PaxDb; Q5BJS9; -.
DR   PRIDE; Q5BJS9; -.
DR   Ensembl; ENSRNOT00000037490; ENSRNOP00000032408; ENSRNOG00000027156.
DR   GeneID; 293950; -.
DR   KEGG; rno:293950; -.
DR   UCSC; RGD:1307336; rat.
DR   CTD; 118812; -.
DR   RGD; 1307336; Morn4.
DR   eggNOG; KOG0231; Eukaryota.
DR   GeneTree; ENSGT00730000111173; -.
DR   HOGENOM; CLU_113346_0_0_1; -.
DR   InParanoid; Q5BJS9; -.
DR   OMA; WFPDGAK; -.
DR   OrthoDB; 1532474at2759; -.
DR   PhylomeDB; Q5BJS9; -.
DR   TreeFam; TF323893; -.
DR   PRO; PR:Q5BJS9; -.
DR   Proteomes; UP000002494; Chromosome 1.
DR   Bgee; ENSRNOG00000027156; Expressed in testis and 19 other tissues.
DR   ExpressionAtlas; Q5BJS9; baseline and differential.
DR   Genevisible; Q5BJS9; RN.
DR   GO; GO:0042995; C:cell projection; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0032433; C:filopodium tip; ISS:UniProtKB.
DR   GO; GO:0032426; C:stereocilium tip; ISS:UniProtKB.
DR   GO; GO:0048678; P:response to axon injury; ISS:UniProtKB.
DR   InterPro; IPR003409; MORN.
DR   Pfam; PF02493; MORN; 4.
DR   SMART; SM00698; MORN; 4.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Reference proteome; Repeat.
FT   CHAIN           1..146
FT                   /note="MORN repeat-containing protein 4"
FT                   /id="PRO_0000279491"
FT   REPEAT          16..38
FT                   /note="MORN 1"
FT   REPEAT          39..61
FT                   /note="MORN 2"
FT   REPEAT          62..84
FT                   /note="MORN 3"
FT   REPEAT          85..107
FT                   /note="MORN 4"
SQ   SEQUENCE   146 AA;  16238 MW;  A54243B274F70A7A CRC64;
     MTLTKGSFTY SSGEEYRGEW KEGRRHGFGQ LMFADGGTYL GHFENGLFNG FGVLTFSDGS
     RYEGEFSQGK FNGVGVFIRY DNMTFEGEFK NGRVDGFGLL TFPDGSHGLP RNEGLFENNK
     LLRREKCSAV VQRAQSASKS ARNLTA
 
 
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