6PGL_PHOLL
ID 6PGL_PHOLL Reviewed; 328 AA.
AC Q7N6R1;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=6-phosphogluconolactonase {ECO:0000255|HAMAP-Rule:MF_01605};
DE Short=6-P-gluconolactonase {ECO:0000255|HAMAP-Rule:MF_01605};
DE EC=3.1.1.31 {ECO:0000255|HAMAP-Rule:MF_01605};
GN Name=pgl {ECO:0000255|HAMAP-Rule:MF_01605}; OrderedLocusNames=plu1480;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-
CC phosphogluconate. {ECO:0000255|HAMAP-Rule:MF_01605}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01605};
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 2/3. {ECO:0000255|HAMAP-Rule:MF_01605}.
CC -!- SIMILARITY: Belongs to the cycloisomerase 2 family. {ECO:0000255|HAMAP-
CC Rule:MF_01605}.
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DR EMBL; BX571864; CAE13773.1; -; Genomic_DNA.
DR RefSeq; WP_011145783.1; NC_005126.1.
DR AlphaFoldDB; Q7N6R1; -.
DR SMR; Q7N6R1; -.
DR STRING; 243265.plu1480; -.
DR PRIDE; Q7N6R1; -.
DR EnsemblBacteria; CAE13773; CAE13773; plu1480.
DR GeneID; 24167140; -.
DR KEGG; plu:plu1480; -.
DR eggNOG; COG2706; Bacteria.
DR HOGENOM; CLU_038716_2_0_6; -.
DR OMA; EGNWPRD; -.
DR OrthoDB; 302683at2; -.
DR BioCyc; PLUM243265:PLU_RS07485-MON; -.
DR UniPathway; UPA00115; UER00409.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.130.10.10; -; 1.
DR HAMAP; MF_01605; 6P_gluconolactonase; 1.
DR InterPro; IPR022528; 6-phosphogluconolactonase_YbhE.
DR InterPro; IPR019405; Lactonase_7-beta_prop.
DR InterPro; IPR011045; N2O_reductase_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR Pfam; PF10282; Lactonase; 1.
DR SUPFAM; SSF50974; SSF50974; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism; Glucose metabolism; Hydrolase; Reference proteome.
FT CHAIN 1..328
FT /note="6-phosphogluconolactonase"
FT /id="PRO_0000171136"
SQ SEQUENCE 328 AA; 36427 MW; 5B09687ABA289EB0 CRC64;
MKQVVYTASP NSCQIHVWSL NNEGELSLIQ TVDVPGEVQP MVVSPDRKHL YVGIRPQFSI
VTYQIGSRGE LAQQGISSIP GSPTHISTDK QGRFLFSASY SYNNLSVSLI DDQGIVGEPV
QVIAGLQAPH SANIDWDNKQ LLVPCLKEDR VRIFEMAKEG YLTEKRAEEI TTAMGAGPRH
MAFHPNQQVI YCINELDSTV DVYRKWEKYR TVQTVDSLPA DLAGVRWSAD IHITPDGRHL
YTSERTSSLI SHFVISQDGS NLTLAGHYKT EIQPRGFAID HSGKYLIASG QKSDHISVSS
IDKYTGKLTE LTRYPVGKGP MWVTVLAL
