MOS11_ARATH
ID MOS11_ARATH Reviewed; 214 AA.
AC Q9LZ08;
DT 19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Protein MODIFIER OF SNC1 11;
GN Name=MOS11; OrderedLocusNames=At5g02770; ORFNames=F9G14.80;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-76, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-76, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=21203492; DOI=10.1371/journal.pgen.1001250;
RA Germain H., Qu N., Cheng Y.T., Lee E., Huang Y., Dong O.X., Gannon P.,
RA Huang S., Ding P., Li Y., Sack F., Zhang Y., Li X.;
RT "MOS11: a new component in the mRNA export pathway.";
RL PLoS Genet. 6:E1001250-E1001250(2010).
RN [8]
RP INTERACTION WITH RH15 AND RH56.
RX PubMed=23555998; DOI=10.1371/journal.pone.0060644;
RA Kammel C., Thomaier M., Sorensen B.B., Schubert T., Langst G., Grasser M.,
RA Grasser K.D.;
RT "Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as
RT well as with mRNA export factors.";
RL PLoS ONE 8:E60644-E60644(2013).
CC -!- FUNCTION: Contributes to the transfer of mature mRNA from the nucleus
CC to the cytosol. May function before mRNAs enter nuclear pore and in the
CC same mRNA export pathway as MOS3. {ECO:0000269|PubMed:21203492}.
CC -!- SUBUNIT: Interacts with RH15 and RH56. {ECO:0000269|PubMed:23555998}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000269|PubMed:21203492}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:21203492}.
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DR EMBL; AL162973; CAB86031.1; -; Genomic_DNA.
DR EMBL; CP002688; AED90515.1; -; Genomic_DNA.
DR EMBL; AF378893; AAK55696.1; -; mRNA.
DR EMBL; AY050475; AAK91488.1; -; mRNA.
DR EMBL; AK221715; BAD95440.1; -; mRNA.
DR PIR; T48298; T48298.
DR RefSeq; NP_195897.1; NM_120355.3.
DR AlphaFoldDB; Q9LZ08; -.
DR SMR; Q9LZ08; -.
DR BioGRID; 16531; 1.
DR STRING; 3702.AT5G02770.1; -.
DR iPTMnet; Q9LZ08; -.
DR PaxDb; Q9LZ08; -.
DR PRIDE; Q9LZ08; -.
DR ProteomicsDB; 238308; -.
DR EnsemblPlants; AT5G02770.1; AT5G02770.1; AT5G02770.
DR GeneID; 831253; -.
DR Gramene; AT5G02770.1; AT5G02770.1; AT5G02770.
DR KEGG; ath:AT5G02770; -.
DR Araport; AT5G02770; -.
DR TAIR; locus:2151271; AT5G02770.
DR eggNOG; ENOG502S2BB; Eukaryota.
DR HOGENOM; CLU_095564_0_0_1; -.
DR InParanoid; Q9LZ08; -.
DR OMA; NDTKADA; -.
DR OrthoDB; 1556864at2759; -.
DR PhylomeDB; Q9LZ08; -.
DR PRO; PR:Q9LZ08; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LZ08; baseline and differential.
DR Genevisible; Q9LZ08; AT.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:TAIR.
DR InterPro; IPR044209; MOS11.
DR InterPro; IPR040746; THO1_MOS11_C.
DR PANTHER; PTHR47701; PTHR47701; 1.
DR Pfam; PF18592; Tho1_MOS11_C; 1.
PE 1: Evidence at protein level;
KW mRNA transport; Nucleus; Phosphoprotein; Reference proteome; RNA-binding;
KW Transport.
FT CHAIN 1..214
FT /note="Protein MODIFIER OF SNC1 11"
FT /id="PRO_0000425593"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..186
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 76
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19245862,
FT ECO:0007744|PubMed:19376835"
SQ SEQUENCE 214 AA; 22779 MW; 2307B981E9297ADE CRC64;
MATNGEKVTA TVVNGGGLST GENPKKIVDL NTTELDRTDD ILDGEVKGFS DSGEKKEETD
SNGIGSTAGV DSGDISPVDD IQKKIRRAER FGVSVKLTEE EKRNSRAERF GTVAAAVVNG
SEGTKKAEEL KRKARADRFG VPSATSTTDK TEEEAKKKAR LARFGKETKV DSAEENKRKA
RALRFSKEAS ADASSDLPEK QIIGKEAAVS GSAA
