MOS1_ARATH
ID MOS1_ARATH Reviewed; 1412 AA.
AC Q9SB63; D9IVG9; F4JR07; Q8W4I1;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2010, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Protein MODIFIER OF SNC1 1;
DE AltName: Full=MODIFIER OF snc1, 1;
GN Name=MOS1; OrderedLocusNames=At4g24680; ORFNames=F22K18.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=20439546; DOI=10.1104/pp.110.156240;
RA Li Y., Tessaro M.J., Li X., Zhang Y.;
RT "Regulation of the expression of plant Resistance gene SNC1 by a protein
RT with a conserved BAT2 domain.";
RL Plant Physiol. 153:1425-1434(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 878-1412.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-72 AND SER-883, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [6]
RP INTERACTION WITH TCP14 AND TCP15.
RX PubMed=29086441; DOI=10.1111/tpj.13757;
RA Zhang N., Wang Z., Bao Z., Yang L., Wu D., Shu X., Hua J.;
RT "MOS1 functions closely with TCP transcription factors to modulate immunity
RT and cell cycle in Arabidopsis.";
RL Plant J. 93:66-78(2018).
CC -!- FUNCTION: Involved in the regulation of the chromatin structure and DNA
CC methylation at the SNC1 locus. Regulates the expression of SNC1 at
CC chromatin level. {ECO:0000269|PubMed:20439546}.
CC -!- SUBUNIT: Interacts with TCP14 and TCP15. {ECO:0000269|PubMed:29086441}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:20439546}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL32626.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AEE84942.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAA22995.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79378.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; HM208348; ADI87413.1; -; mRNA.
DR EMBL; AL035356; CAA22995.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161562; CAB79378.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84942.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; ANM67216.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM67218.1; -; Genomic_DNA.
DR EMBL; AY062548; AAL32626.1; ALT_INIT; mRNA.
DR EMBL; AY093339; AAM13338.1; -; mRNA.
DR PIR; T05566; T05566.
DR RefSeq; NP_001329059.1; NM_001341694.1.
DR RefSeq; NP_001329061.1; NM_001341692.1.
DR RefSeq; NP_194199.4; NM_118601.5.
DR AlphaFoldDB; Q9SB63; -.
DR SMR; Q9SB63; -.
DR BioGRID; 13859; 8.
DR IntAct; Q9SB63; 6.
DR STRING; 3702.AT4G24680.1; -.
DR iPTMnet; Q9SB63; -.
DR PaxDb; Q9SB63; -.
DR PRIDE; Q9SB63; -.
DR ProteomicsDB; 250940; -.
DR EnsemblPlants; AT4G24680.3; AT4G24680.3; AT4G24680.
DR EnsemblPlants; AT4G24680.5; AT4G24680.5; AT4G24680.
DR GeneID; 828570; -.
DR Gramene; AT4G24680.3; AT4G24680.3; AT4G24680.
DR Gramene; AT4G24680.5; AT4G24680.5; AT4G24680.
DR KEGG; ath:AT4G24680; -.
DR Araport; AT4G24680; -.
DR eggNOG; ENOG502SF51; Eukaryota.
DR HOGENOM; CLU_252180_0_0_1; -.
DR InParanoid; Q9SB63; -.
DR OrthoDB; 126119at2759; -.
DR PhylomeDB; Q9SB63; -.
DR PRO; PR:Q9SB63; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SB63; baseline and differential.
DR Genevisible; Q9SB63; AT.
DR GO; GO:0040029; P:regulation of gene expression, epigenetic; IBA:GO_Central.
DR InterPro; IPR009738; BAT2_N.
DR InterPro; IPR038808; MOS1-like.
DR PANTHER; PTHR34805; PTHR34805; 1.
DR Pfam; PF07001; BAT2_N; 1.
PE 1: Evidence at protein level;
KW Chromatin regulator; Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..1412
FT /note="Protein MODIFIER OF SNC1 1"
FT /id="PRO_0000399941"
FT REGION 1..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 667..717
FT /evidence="ECO:0000255"
FT COMPBIAS 55..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..713
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..783
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 827..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..1003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1004..1018
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1027..1074
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1103..1141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1190..1205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1261..1312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1328..1348
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1355..1377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1386..1402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 72
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
FT MOD_RES 883
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19376835"
FT CONFLICT 1083
FT /note="G -> S (in Ref. 2; AAL32626)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1412 AA; 153687 MW; D394A8727C3500CF CRC64;
MTSSTTGDRR WGTTRRSGMT ILGKVAVPKP INLPSQRLEN QGLDPNVEIV PKGTLSWGSK
SSLNAWGTSS LSPRTESGPG SPSHLSNRPS SGGSVTRPST ADSNKAHDSS SSVAWDSNSR
PSSASGVFPS NQPSVALQRP HSADTRPGSS QLSRFAEPVS ETSATWGQHV APEKLGVAPS
KNDGFSLTSG DFPSLGAEKD TSEKSTRPQD AGPHARPPSS SGRSVEGQGV DCTEEANDRI
GDANSWRREN QPYSEDAPRH CREEGQLDSR GSQSYPNANF PPRYDAWRGP PVNNHQGGGW
YGGNHPYGAP MGPGGFHMDP FPFYPTQVPP APGHGAGPRG NHANNERMFR PPMLDSYVHP
RMQTRPGFYV GPAPHEGYYG PPMGYGSPSN RDLPFAGRPT GPHAYNNHSG QGGYDTPGSS
VSLERNESSH SQETQRPYKV LLKHQDGRFG EDNAKREEFL GNRLPNAEKI AQQMQTSRNE
RREIRNDASG EVQPVKAELA APGDPSLIQK IEGLNAKTRT NDGWQNSSSV VNRDEQESQP
RTLNSGNSAN KVSARNHRTG HASDSKNSSH YNQGDSATNK NAEPAAMGGT SIFRRPTQQT
QGRADPQTKR IVNSEGNDAW QKTTVMSGSS HTTLATNTES FREVNVDDSL DTESIRRPGS
GISADPKDNQ RSTMRELARQ RAQQRQKEEE ERARDQRAKA LAKLEELNRR SQIYEEGSVK
NMEAASNASP ADMPTDPGSH SSNATNSVEP TGGSGKNTTQ NTRTSTEYAN NVGPSQQDNL
PRDGGASKQK RLGYKQKQNI IFEKKPTGSS VATAEVFDVV PSPEVVNEGV SSNNSDMPAT
STVSAESTFP KRKNNRNGKK KHKAEETATM NTTRVAVGKE TKSGDESIET ARARAAEIEL
GSVSVPSLDI KVSGDSSEQI SSFTNEESQN RAKNNWKSQH VRRTQRNSLV NKPAEKFSGN
NAVIWAPVHP QQKADVSTGG GSQTTVPEFG TSSKSQHQGQ TSSKSKRVEI ERYVPKPIVK
EMAEQIVSKN LVTSAPDMSE NVNQKENRGG EGTGILQPSG STAGKSGSPS KSRHGNGRQG
KHGREHASWH QRGSGAPTKA LEDGQFVTSN QPIRGTVNYH SSKQTEQIAA KDQTTCNKDG
WNDGWYMTPE THYSAAEEME SSAVGKDQGM SMHGRQHASR SNKDGGSNYG DPKKGNKRDF
NKAHTQHSGH GFSQPDLPAA SKEGRVPGDH VWHTANRTGK YGGRESTRDK PYGSQEKNVV
GYEHQGFTTE QKTTSADTQA QLQNRSTNKE VQVEQNPNSM FQKNTGQGRR FGRGQESQGG
WGLPAQENMH HHHQRPPSNR DRQKQNLHYE YKPVGSHTYD GERSREQSKE SSQTEGPRYR
EKGQGQQRQG GYQQQRGTSG RNGGHGFTGD RN
