ID   MOSA_MAIZE              Reviewed;         621 AA.
AC   P15268;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Autonomous transposable element EN-1 mosaic protein;
DE   AltName: Full=Suppressor-mutator system protein;
DE            Short=SPM;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15957213; DOI=10.1002/j.1460-2075.1986.tb04292.x;
RA   Pereira A., Cuypers H., Gierl A., Schwarz-Sommer Z., Saedler H.;
RT   "Molecular analysis of the En/Spm transposable element system of Zea
RT   mays.";
RL   EMBO J. 5:835-841(1986).
CC   -!- FUNCTION: This protein has most probably three functions; the mutator
CC       (M) function, for excision and transposition; the suppressor (S)
CC       function, which inhibits residual gene activity of certain alleles in
CC       which inhibitor elements are integrated; an activator (A) function is
CC       proposed, because inactive SPM can be activated by a second SPM.
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DR   EMBL; M25427; AAA66268.1; -; Genomic_DNA.
DR   PIR; S28365; S28365.
DR   AlphaFoldDB; P15268; -.
DR   SMR; P15268; -.
DR   PRIDE; P15268; -.
DR   MaizeGDB; 65370; -.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P15268; baseline and differential.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   InterPro; IPR039266; EN-1/SPM.
DR   InterPro; IPR004252; Probable_transposase_24.
DR   PANTHER; PTHR33157; PTHR33157; 1.
DR   Pfam; PF03004; Transposase_24; 1.
PE   2: Evidence at transcript level;
KW   Activator; Mutator protein; Reference proteome; Repressor; Transcription;
KW   Transcription regulation; Transposable element; Transposition.
FT   CHAIN           1..621
FT                   /note="Autonomous transposable element EN-1 mosaic protein"
FT                   /id="PRO_0000096541"
FT   REGION          1..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          428..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          498..530
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          549..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..104
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        503..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        549..571
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        575..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   621 AA;  68362 MW;  54B930960EB774AA CRC64;
     MFRMDSSGRR SRSRRSRGSS GAPNMFEGTT TSRSRQEQLL ASLEQMRGSS GPSNTEGTTS
     RAADLVAPTM APTAEAAVDA EAAVDAEAEE AAAELDDGEE TSGADASTEE AATQAPPRRA
     IRYRRSLTLK PSKPFDQRRV IEPKGTRAWK EVSWDGTGHR TPILTELGIC LRFAYPAMVT
     EGGQEIAAHY WAHWDLKPYG NDGTHTSKVW DLFWGQFRVC DPYTLDDSYV REVFNGSADR
     AVKGMMYKAR LRAVTVYQKR QGNYCDANMA KEIHLTAQQY KESEVDWLSH HSDAWAWMCE
     YWASEEFLAI SNRNRMNRLS KPGVHFFGAD GHVGKAARMA ARNGVEPTLL QVFVEGHKGP
     DPNHPEILND SNATEKLARY IDNVREKNGP DTDWLTGEFD TEAAYKAGGG VPHGRLAIGD
     GVVPRRSYTR RSNFSAGSNR PRRPSAREGE LLEKMTQMEE SMAQYKQQVQ QQMQQMQNWM
     LHQMYGGAGT QFGMPPFQQP PIITHPVSGQ SSDRSTAAAD GSQGSATSVQ DQLMPLGVIG
     GQMMPWAPRQ PGIWPPMQTQ MPPPMPWGFP PRGQSQSPGL PSHSPGSGSG SHHASPPPDQ
     STFMDLLMNT SGGGSNDPPT E