ID   MOT13_BOVIN             Reviewed;         426 AA.
AC   Q17QR6;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Monocarboxylate transporter 13;
DE            Short=MCT 13;
DE   AltName: Full=Solute carrier family 16 member 13;
GN   Name=SLC16A13; Synonyms=MCT13;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Proton-linked monocarboxylate transporter. May catalyze the
CC       transport of monocarboxylates across the plasma membrane.
CC       {ECO:0000250|UniProtKB:Q7RTY0}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q7RTY0}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q7RTY0}. Cell membrane {ECO:0000255}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       Monocarboxylate porter (TC 2.A.1.13) family. {ECO:0000305}.
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DR   EMBL; BC118219; AAI18220.1; -; mRNA.
DR   RefSeq; NP_001069600.1; NM_001076132.1.
DR   AlphaFoldDB; Q17QR6; -.
DR   SMR; Q17QR6; -.
DR   STRING; 9913.ENSBTAP00000027786; -.
DR   PaxDb; Q17QR6; -.
DR   PRIDE; Q17QR6; -.
DR   Ensembl; ENSBTAT00000027786; ENSBTAP00000027786; ENSBTAG00000020853.
DR   GeneID; 538855; -.
DR   KEGG; bta:538855; -.
DR   CTD; 201232; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020853; -.
DR   VGNC; VGNC:34687; SLC16A13.
DR   eggNOG; KOG2504; Eukaryota.
DR   GeneTree; ENSGT00940000159372; -.
DR   HOGENOM; CLU_001265_59_1_1; -.
DR   InParanoid; Q17QR6; -.
DR   OMA; YGMTEVQ; -.
DR   OrthoDB; 916876at2759; -.
DR   TreeFam; TF313792; -.
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000020853; Expressed in liver and 101 other tissues.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015718; P:monocarboxylic acid transport; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Golgi apparatus; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..426
FT                   /note="Monocarboxylate transporter 13"
FT                   /id="PRO_0000287186"
FT   TOPO_DOM        1..10
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        306..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        395..426
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   426 AA;  44713 MW;  4F5901D183B048C5 CRC64;
     MAYRAEPPDG GWGWMVVLSA FFQSALVFGV LRSFGVFFVE FVAAFEEPAA RVSWIASIGI
     AVQQFGSPVG SALSTKFGPR PAVMTGGILT ALGMLLASFA TSLTHLYLSI GLLSGSGWAL
     TFTPTLACLS RYFSRRRSLA MGLALTGVGL SSFAFAPLFQ WLLNHYAWRG ALLLVSALSL
     HLVACGALLR PLSLAEDPVV GGPGAQITSL LRHGPFLRYT VALTLINTGY FIPYVHLVAH
     LRDLGWDPLP AAFLLSVAAI SDLVGRVASG WLGDAVPGPV ARLLMLWTTL TGVILALYPV
     AEAPTGLVAL TMAYGFTSGA LTPVAFSVLP ELVGTGKIYC GLGLVQMVES IGGLLGAPLS
     GYLRDVTGNY TASFVVAGAF LLAGSGVLIT LPHFFCFSAP TSKPQDLVTE ALDTKVPLPE
     EGLGED