MOTA_AGRFC
ID MOTA_AGRFC Reviewed; 290 AA.
AC Q44456;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Motility protein A;
DE AltName: Full=Chemotaxis protein MotA;
GN Name=motA; OrderedLocusNames=Atu0560; ORFNames=AGR_C_985;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9161425; DOI=10.1016/s0378-1119(96)00853-0;
RA Deakin W.J., Parker V.E., Loake G.J., Shaw C.H.;
RT "The Agrobacterium tumefaciens motor gene, motA, is in a linked cluster
RT with the flagellar switch protein genes, fliG, fliM and fliN.";
RL Gene 189:139-141(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: MotA and MotB comprise the stator element of the flagellar
CC motor complex. Required for rotation of the flagellar motor. Probable
CC transmembrane proton channel (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Each stator complex is composed of 4 MotA and 2 MotB subunits.
CC 2 A subunits and 1 B subunit are thought to form a single ion channel,
CC so that each stator complex contains two channels (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MotA family. {ECO:0000305}.
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DR EMBL; U63290; AAC45321.1; -; Genomic_DNA.
DR EMBL; U95165; AAB71782.1; -; Genomic_DNA.
DR EMBL; AE007869; AAK86372.1; -; Genomic_DNA.
DR PIR; AC2645; AC2645.
DR PIR; C97427; C97427.
DR RefSeq; NP_353587.1; NC_003062.2.
DR RefSeq; WP_006313025.1; NC_003062.2.
DR AlphaFoldDB; Q44456; -.
DR SMR; Q44456; -.
DR STRING; 176299.Atu0560; -.
DR EnsemblBacteria; AAK86372; AAK86372; Atu0560.
DR GeneID; 66220729; -.
DR KEGG; atu:Atu0560; -.
DR PATRIC; fig|176299.10.peg.556; -.
DR eggNOG; COG1291; Bacteria.
DR HOGENOM; CLU_068213_0_0_5; -.
DR OMA; EIETHHQ; -.
DR PhylomeDB; Q44456; -.
DR BioCyc; AGRO:ATU0560-MON; -.
DR Proteomes; UP000000813; Chromosome circular.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IMP:GO_Central.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR000540; Flag_MotA_CS.
DR InterPro; IPR022522; Flagellar_motor_stator_MotA.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR PANTHER; PTHR30433:SF4; PTHR30433:SF4; 1.
DR Pfam; PF01618; MotA_ExbB; 1.
DR TIGRFAMs; TIGR03818; MotA1; 1.
DR PROSITE; PS01307; MOTA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Chemotaxis; Flagellar rotation;
KW Hydrogen ion transport; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..290
FT /note="Motility protein A"
FT /id="PRO_0000189568"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 290 AA; 31529 MW; 639C44CFDF40BC81 CRC64;
MNIVIGLIIT FGCIIGGYMA MGGHLNVLVQ PFELMIIGGA GLGGFIMANP MKVVKDSGKA
LGEAFKHSVP KERNYLDVLG VLYSLMRDLR TKSRNEIEAH IDNPEESSIF QSAPSVLKNK
ELTSFICDYV RLIIIGNARS HEIEALMDEE IETILHDKLK PYHAITTMGD SFPAIGIVAA
VLGVIKAMGK INESPEVLGG LIGAALVGTM LGIILSYSIC NPLASQVKIV RTKQHRLYII
VKQTLIAYMN GSVPQVALEY GRKTISNYER PSIDAVEQEM MNPGGENKAA