ID   MOTA_HELPY              Reviewed;         257 AA.
AC   P65410; P56426;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Motility protein A;
DE   AltName: Full=Chemotaxis protein MotA;
GN   Name=motA; OrderedLocusNames=HP_0815;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: MotA and MotB comprise the stator element of the flagellar
CC       motor complex. Required for rotation of the flagellar motor. Probable
CC       transmembrane proton channel (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Each stator complex is composed of 4 MotA and 2 MotB subunits.
CC       2 A subunits and 1 B subunit are thought to form a single ion channel,
CC       so that each stator complex contains two channels (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MotA family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD07864.1; -; Genomic_DNA.
DR   PIR; G64621; G64621.
DR   RefSeq; NP_207608.1; NC_000915.1.
DR   RefSeq; WP_000366185.1; NC_018939.1.
DR   AlphaFoldDB; P65410; -.
DR   SMR; P65410; -.
DR   STRING; 85962.C694_04175; -.
DR   PaxDb; P65410; -.
DR   EnsemblBacteria; AAD07864; AAD07864; HP_0815.
DR   GeneID; 66522033; -.
DR   KEGG; hpy:HP_0815; -.
DR   PATRIC; fig|85962.47.peg.868; -.
DR   eggNOG; COG1291; Bacteria.
DR   OMA; ANLIWLN; -.
DR   PhylomeDB; P65410; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IBA:GO_Central.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR000540; Flag_MotA_CS.
DR   InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR   Pfam; PF01618; MotA_ExbB; 1.
DR   PROSITE; PS01307; MOTA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Chemotaxis; Flagellar rotation;
KW   Hydrogen ion transport; Ion transport; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..257
FT                   /note="Motility protein A"
FT                   /id="PRO_0000189574"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        201..257
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   257 AA;  27710 MW;  528CF6057F974B86 CRC64;
     MDLSTILGLV LAVASISLGD ILEDGNPLHI IHLSSVIIIV PTSLFAAMTG THARYVKAAY
     KEIKIVFLNP KINLNETIKN LVELATLARK DGVLSLEGRV AQIEDDFTRN GLSMIIDGKD
     LKSVKESLEI SIEEMEEYYH GAAHYWETAG ETAPTMGLVG AVMGLMLALQ KLDNPAEMAA
     GIAGAFTATV TGIMCSYAIF GPFGHKLKAK SKDIIKEKTV LLEGILGIAN GENPRDLENK
     LLNYIAPGEP KKSQFEG