MOTA_RHIME
ID MOTA_RHIME Reviewed; 292 AA.
AC P97215;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2001, sequence version 3.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Motility protein A;
DE AltName: Full=Chemotaxis protein MotA;
GN Name=motA; OrderedLocusNames=R00654; ORFNames=SMc03022;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=RU11/001;
RA Schmitt R., Sterr W.;
RT "Rhizobium meliloti MotA gene.";
RL Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=RU11/001;
RX PubMed=9858749; DOI=10.1016/s0378-1119(98)00160-7;
RA Sourjik V., Sterr W., Platzer J., Bos I., Haslbeck M., Schmitt R.;
RT "Mapping of 41 chemotaxis, flagellar and motility genes to a single region
RT of the Sinorhizobium meliloti chromosome.";
RL Gene 223:283-290(1998).
RN [3]
RP SEQUENCE REVISION TO 198.
RA Scharf B.;
RL Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=RCR2011 / SU47;
RA Hazelbauer G.L., Daley I.J., Dutton D.P., Lilly A.A.;
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: MotA and MotB comprise the stator element of the flagellar
CC motor complex. Required for rotation of the flagellar motor. Probable
CC transmembrane proton channel (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Each stator complex is composed of 4 MotA and 2 MotB subunits.
CC 2 A subunits and 1 B subunit are thought to form a single ion channel,
CC so that each stator complex contains two channels (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MotA family. {ECO:0000305}.
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DR EMBL; U87913; AAB47573.1; -; Genomic_DNA.
DR EMBL; AJ224445; CAA11955.2; -; Genomic_DNA.
DR EMBL; U87146; AAB48837.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45226.1; -; Genomic_DNA.
DR RefSeq; NP_384760.1; NC_003047.1.
DR RefSeq; WP_003529914.1; NC_003047.1.
DR AlphaFoldDB; P97215; -.
DR SMR; P97215; -.
DR STRING; 266834.SMc03022; -.
DR EnsemblBacteria; CAC45226; CAC45226; SMc03022.
DR GeneID; 61602121; -.
DR KEGG; sme:SMc03022; -.
DR PATRIC; fig|266834.11.peg.2028; -.
DR eggNOG; COG1291; Bacteria.
DR HOGENOM; CLU_068213_0_0_5; -.
DR OMA; EIETHHQ; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR000540; Flag_MotA_CS.
DR InterPro; IPR022522; Flagellar_motor_stator_MotA.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR PANTHER; PTHR30433:SF4; PTHR30433:SF4; 1.
DR Pfam; PF01618; MotA_ExbB; 1.
DR TIGRFAMs; TIGR03818; MotA1; 1.
DR PROSITE; PS01307; MOTA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Chemotaxis; Flagellar rotation;
KW Hydrogen ion transport; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..292
FT /note="Motility protein A"
FT /id="PRO_0000189576"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 141
FT /note="H -> Y (in Ref. 2; CAA11955)"
FT /evidence="ECO:0000305"
FT CONFLICT 198
FT /note="L -> V (in Ref. 1; AAB47573 and 4; AAB48837)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 292 AA; 31577 MW; 464A01F285883840 CRC64;
MNIIIGLLVT FGCILGGYMA MGGHLEVLNQ PFELMIIGGA GIGGFIMANS MKVVKDTGKA
LGEAFRHKVP KEREYLDTLG VLYSLMRDLR TKSRNEIESH IDNPEESSIF QSAPTVLQNK
ELTAFICDYV RLIIIGNARS HEIEALMDEE IQTITHDKMK CYHAMTTMGD ALPAIGIVAA
VLGVIKAMGA ISEAPEVLGA KIAAALVGTL LGVFLSYSIV GPLVANIKSV REKQNRLYVI
VKQTLLAYMN GSVPQVALEY GRKTISAYER PSIDAVEQEM MNPGGGSESK AA
