MOTB_HELPJ
ID MOTB_HELPJ Reviewed; 257 AA.
AC Q9ZL29;
DT 08-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Motility protein B;
DE AltName: Full=Chemotaxis protein MotB;
GN Name=motB; OrderedLocusNames=jhp_0752;
OS Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J99 / ATCC 700824;
RX PubMed=9923682; DOI=10.1038/16495;
RA Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT "Genomic sequence comparison of two unrelated isolates of the human gastric
RT pathogen Helicobacter pylori.";
RL Nature 397:176-180(1999).
CC -!- FUNCTION: MotA and MotB comprise the stator element of the flagellar
CC motor complex. Required for the rotation of the flagellar motor. Might
CC be a linker that fastens the torque-generating machinery to the cell
CC wall (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Each stator complex is composed of 4 MotA and 2 MotB subunits.
CC 2 A subunits and 1 B subunit are thought to form a single ion channel,
CC so that each stator complex contains two channels (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC type II membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MotB family. {ECO:0000305}.
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DR EMBL; AE001439; AAD06331.1; -; Genomic_DNA.
DR PIR; B71892; B71892.
DR RefSeq; WP_001085351.1; NZ_CP011330.1.
DR AlphaFoldDB; Q9ZL29; -.
DR SMR; Q9ZL29; -.
DR STRING; 85963.jhp_0752; -.
DR EnsemblBacteria; AAD06331; AAD06331; jhp_0752.
DR KEGG; hpj:jhp_0752; -.
DR PATRIC; fig|85963.30.peg.224; -.
DR eggNOG; COG1360; Bacteria.
DR OMA; NWHLSSA; -.
DR Proteomes; UP000000804; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR CDD; cd07185; OmpA_C-like; 1.
DR Gene3D; 3.30.1330.60; -; 1.
DR InterPro; IPR025713; MotB_N_dom.
DR InterPro; IPR006665; OmpA-like.
DR InterPro; IPR036737; OmpA-like_sf.
DR Pfam; PF13677; MotB_plug; 1.
DR Pfam; PF00691; OmpA; 1.
DR SUPFAM; SSF103088; SSF103088; 1.
DR PROSITE; PS51123; OMPA_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Chemotaxis; Flagellar rotation;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..257
FT /note="Motility protein B"
FT /id="PRO_0000189589"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..257
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 113..236
FT /note="OmpA-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
FT REGION 74..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 257 AA; 28838 MW; 04F8E7BF7833A9FB CRC64;
MAKKNKPTEC PAGEKWAVPY ADFLSLLLAL FIALYAISAV NKSKVEALKT EFIKIFNYAP
KPEAMQPVVV IPPDSGKEEE QMASESSKPA SQNTETKATI ARKGEGSVLE QIDQGSVLKL
PSSLLFENAT SDAINQDMML YIERIAKIIQ KLPKRVHINV RGFTDNTPLN KTRFKSHYEL
AANRAYRVMK VLIQYGVDPN QLSFSSYGST NPIAPNDSLE NRMKNNRVEI FFSTDANDLS
KIHSILDEEF NPHKQQE
