MOTB_SALTY
ID MOTB_SALTY Reviewed; 309 AA.
AC P55892; Q9RM65;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Motility protein B;
DE AltName: Full=Chemotaxis protein MotB;
GN Name=motB; OrderedLocusNames=STM1922;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SJW1103;
RX PubMed=9139919; DOI=10.1128/jb.179.9.2994-3003.1997;
RA Togashi F., Yamaguchi S., Kihara M., Aizawa S., Macnab R.M.;
RT "An extreme clockwise switch bias mutation in fliG of Salmonella
RT typhimurium and its suppression by slow-motile mutations in motA and
RT motB.";
RL J. Bacteriol. 179:2994-3003(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-176.
RX PubMed=10586519; DOI=10.1266/ggs.74.105;
RA Yanagihara S., Iyoda S., Ohnishi K., Iino T., Kutsukake K.;
RT "Structure and transcriptional control of the flagellar master operon of
RT Salmonella typhimurium.";
RL Genes Genet. Syst. 74:105-111(1999).
CC -!- FUNCTION: MotA and MotB comprise the stator element of the flagellar
CC motor complex. Required for the rotation of the flagellar motor. Might
CC be a linker that fastens the torque-generating machinery to the cell
CC wall (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Each stator complex is composed of 4 MotA and 2 MotB subunits.
CC 2 A subunits and 1 B subunit are thought to form a single ion channel,
CC so that each stator complex contains two channels (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC type II membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MotB family. {ECO:0000305}.
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DR EMBL; U81861; AAC45266.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20838.1; -; Genomic_DNA.
DR EMBL; D43640; BAA85317.1; -; Genomic_DNA.
DR RefSeq; NP_460879.1; NC_003197.2.
DR RefSeq; WP_000795653.1; NC_003197.2.
DR PDB; 2ZOV; X-ray; 2.00 A; A=88-291.
DR PDB; 2ZVY; X-ray; 1.75 A; A/B=99-276.
DR PDB; 2ZVZ; X-ray; 2.40 A; A/B=99-276.
DR PDB; 5Y3Z; X-ray; 2.00 A; A/B=99-276.
DR PDB; 5Y40; X-ray; 2.80 A; A/B/C/D=99-276.
DR PDBsum; 2ZOV; -.
DR PDBsum; 2ZVY; -.
DR PDBsum; 2ZVZ; -.
DR PDBsum; 5Y3Z; -.
DR PDBsum; 5Y40; -.
DR AlphaFoldDB; P55892; -.
DR SMR; P55892; -.
DR IntAct; P55892; 1.
DR STRING; 99287.STM1922; -.
DR TCDB; 1.A.30.1.7; the h(+)- or na(+)-translocating bacterial flagellar motor/exbbd outer membrane transport energizer (mot/exb) superfamily.
DR PaxDb; P55892; -.
DR EnsemblBacteria; AAL20838; AAL20838; STM1922.
DR GeneID; 1253443; -.
DR KEGG; stm:STM1922; -.
DR PATRIC; fig|99287.12.peg.2039; -.
DR HOGENOM; CLU_016890_3_0_6; -.
DR OMA; DEKNRPM; -.
DR PhylomeDB; P55892; -.
DR BioCyc; SENT99287:STM1922-MON; -.
DR EvolutionaryTrace; P55892; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR CDD; cd07185; OmpA_C-like; 1.
DR Gene3D; 3.30.1330.60; -; 1.
DR InterPro; IPR025713; MotB_N_dom.
DR InterPro; IPR006665; OmpA-like.
DR InterPro; IPR036737; OmpA-like_sf.
DR Pfam; PF13677; MotB_plug; 1.
DR Pfam; PF00691; OmpA; 1.
DR SUPFAM; SSF103088; SSF103088; 1.
DR PROSITE; PS51123; OMPA_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell inner membrane; Cell membrane; Chemotaxis;
KW Flagellar rotation; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..309
FT /note="Motility protein B"
FT /id="PRO_0000189587"
FT TOPO_DOM 1..28
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 51..309
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 149..269
FT /note="OmpA-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
FT REGION 276..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 101..129
FT /evidence="ECO:0007829|PDB:2ZVY"
FT HELIX 131..134
FT /evidence="ECO:0007829|PDB:2ZVY"
FT HELIX 135..139
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 140..145
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 148..154
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 157..159
FT /evidence="ECO:0007829|PDB:2ZVY"
FT HELIX 171..184
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 187..189
FT /evidence="ECO:0007829|PDB:5Y40"
FT STRAND 191..196
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 206..209
FT /evidence="ECO:0007829|PDB:5Y3Z"
FT HELIX 211..228
FT /evidence="ECO:0007829|PDB:2ZVY"
FT HELIX 233..235
FT /evidence="ECO:0007829|PDB:5Y40"
FT STRAND 236..241
FT /evidence="ECO:0007829|PDB:2ZVY"
FT TURN 243..246
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 249..251
FT /evidence="ECO:0007829|PDB:5Y3Z"
FT HELIX 255..258
FT /evidence="ECO:0007829|PDB:2ZVY"
FT STRAND 259..266
FT /evidence="ECO:0007829|PDB:2ZVY"
FT HELIX 268..276
FT /evidence="ECO:0007829|PDB:2ZVY"
SQ SEQUENCE 309 AA; 34159 MW; 88846FF1D1BB4C29 CRC64;
MKNQAHPIVV VKRRRHKPHG GGAHGSWKIA YADFMTAMMA FFLVMWLISI SSPKELIQIA
EYFRTPLATA VTGGNRIANS ESPIPGGGDD YTQQQGEVEK QPNIDELKKR MEQSRLNKLR
GDLDQLIESD PKLRALRPHL KIDLVQEGLR IQIIDSQNRP MFKTGSAEVE PYMRDILRAI
APVLNGIPNR ISLAGHTDDF PYANGEKGYS NWELSADRAN ASRRELVAGG LDNGKVLRVV
GMAATMRLSD RGPDDAINRR ISLLVLNKQA EQAILHENAE SQNEPVSVLQ QPAAAPPASV
PTSPKAEPR
