ID   MOTB_TREPA              Reviewed;         238 AA.
AC   O07887;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 125.
DE   RecName: Full=Motility protein B;
DE   AltName: Full=Chemotaxis protein MotB;
GN   Name=motB; OrderedLocusNames=TP_0724;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8755894; DOI=10.1128/jb.178.15.4628-4634.1996;
RA   Limberger R.J., Slivienski L.L., El-Afandi M.C.T., Dantuono L.A.;
RT   "Organization, transcription, and expression of the 5' region of the fla
RT   operon of Treponema phagedenis and Treponema pallidum.";
RL   J. Bacteriol. 178:4628-4634(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: MotA and MotB comprise the stator element of the flagellar
CC       motor complex. Required for the rotation of the flagellar motor. Might
CC       be a linker that fastens the torque-generating machinery to the cell
CC       wall (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Each stator complex is composed of 4 MotA and 2 MotB subunits.
CC       2 A subunits and 1 B subunit are thought to form a single ion channel,
CC       so that each stator complex contains two channels (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC       type II membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MotB family. {ECO:0000305}.
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DR   EMBL; U28219; AAB61254.1; -; Genomic_DNA.
DR   EMBL; AE000520; AAC65689.1; -; Genomic_DNA.
DR   PIR; H71291; H71291.
DR   RefSeq; WP_010882169.1; NC_000919.1.
DR   AlphaFoldDB; O07887; -.
DR   SMR; O07887; -.
DR   IntAct; O07887; 2.
DR   STRING; 243276.TPANIC_0724; -.
DR   EnsemblBacteria; AAC65689; AAC65689; TP_0724.
DR   GeneID; 57879248; -.
DR   KEGG; tpa:TP_0724; -.
DR   eggNOG; COG1360; Bacteria.
DR   HOGENOM; CLU_016890_0_1_12; -.
DR   OMA; NWHLSSA; -.
DR   OrthoDB; 1619550at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   CDD; cd07185; OmpA_C-like; 1.
DR   Gene3D; 3.30.1330.60; -; 1.
DR   InterPro; IPR025713; MotB_N_dom.
DR   InterPro; IPR006665; OmpA-like.
DR   InterPro; IPR036737; OmpA-like_sf.
DR   Pfam; PF13677; MotB_plug; 1.
DR   Pfam; PF00691; OmpA; 1.
DR   SUPFAM; SSF103088; SSF103088; 1.
DR   PROSITE; PS51123; OMPA_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Chemotaxis; Flagellar rotation;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..238
FT                   /note="Motility protein B"
FT                   /id="PRO_0000189590"
FT   TOPO_DOM        1..14
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        15..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        35..238
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          112..236
FT                   /note="OmpA-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
SQ   SEQUENCE   238 AA;  26050 MW;  0AB5FCDBE9852E1F CRC64;
     MARKRRAPRG AAQGWLTTYS DMVTLMLCFF VMLFNPTEVD ITVLQSIAAS IVGDPTGGGV
     SASSGRLADL GNTVNTLPSL EKGQKLATAL KKAVSLFAPE IKSNKIAVTS DERGLVISLT
     SDSFFYPGSS DLNVEESREA LLRVAQFLSD HALAGRRFRI EGHTDSVEVP EDGSTDNWEL
     STRRAVRVLH YLTDFGAQEN RFSLAGYADT RAKFSNESPE GRAYNRRVDI VILDEGHF