ID   MP1_ASPFM               Reviewed;         284 AA.
AC   Q9HFP8; Q4W9Z1;
DT   29-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Cell wall mannoprotein 1 {ECO:0000250|UniProtKB:Q8TG42};
DE   Flags: Precursor;
GN   Name=MP1 {ECO:0000303|PubMed:11682494};
OS   Neosartorya fumigata (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=746128 {ECO:0000312|EMBL:AAG09624.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, GLYCOSYLATION,
RP   AND BIOTECHNOLOGY.
RX   PubMed=11682494; DOI=10.1128/jcm.39.11.3830-3837.2001;
RA   Yuen K.Y., Chan C.M., Chan K.M., Woo P.C., Che X.Y., Leung A.S., Cao L.;
RT   "Characterization of AFMP1: a novel target for serodiagnosis of
RT   aspergillosis.";
RL   J. Clin. Microbiol. 39:3830-3837(2001).
CC   -!- FUNCTION: Constitutive protein of the cell wall. Antigen target of host
CC       humoral immune response. {ECO:0000269|PubMed:11682494}.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000269|PubMed:11682494}. Note=Associated with the entire
CC       thickness of the hyphal cell walls, hyphal septa, and walls of
CC       conidiospores. {ECO:0000269|PubMed:11682494}.
CC   -!- PTM: Galactomannoprotein, glycosylated. {ECO:0000269|PubMed:11682494}.
CC   -!- BIOTECHNOLOGY: May be useful for serodiagnosis in patients with
CC       aspergilloma or invasive aspergillosis. {ECO:0000305|PubMed:11682494}.
CC   -!- SIMILARITY: Belongs to the cell wall mannoprotein 1 family.
CC       {ECO:0000305}.
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DR   EMBL; AY007312; AAG09624.1; -; mRNA.
DR   AlphaFoldDB; Q9HFP8; -.
DR   SMR; Q9HFP8; -.
DR   Allergome; 69; Asp f 17.
DR   OMA; AGECKTV; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0009277; C:fungal-type cell wall; IDA:AspGD.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   InterPro; IPR021054; Cell_wall_mannoprotein_1.
DR   Pfam; PF12296; HsbA; 1.
PE   1: Evidence at protein level;
KW   Cell wall; Lipid-binding; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..284
FT                   /note="Cell wall mannoprotein 1"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000432783"
FT   REGION          176..252
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   284 AA;  27361 MW;  39FEB2B5DB5345E2 CRC64;
     MRFSALLVTL GLTGALATPT LVSREAPAVG VISDISAQTS ALASAVSSYN GGDPSAVKSA
     SEKLVSTINS GVDTVKSGPA LSTADALALT SPVQDLTKQV EGVIDDLISK KDKFVAANAG
     GTVYEDLKAQ YTAADSLAKA ISAKVPESLS DIAAQLSAGI TAAIQKGIDA YKDAASSTGT
     ASSSAPATET ATATETSTAT GTVTETATST PVIPTGTASG SASATPSTTA TPTTGGSGSG
     SGSSTGTATA STSTNLLSTG AASKEHFSYS LGGAVVAAAI AVAL