MP2_MCMVK
ID MP2_MCMVK Reviewed; 64 AA.
AC A0A131KVX9;
DT 25-MAY-2022, integrated into UniProtKB/Swiss-Prot.
DT 11-MAY-2016, sequence version 1.
DT 03-AUG-2022, entry version 10.
DE RecName: Full=p7b {ECO:0000303|PubMed:27242072};
GN ORFNames=ORF4 {ECO:0000305};
OS Maize chlorotic mottle virus (isolate United States/Kansas/1987) (MCMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC Tolivirales; Tombusviridae; Procedovirinae; Machlomovirus.
OX NCBI_TaxID=882210;
OH NCBI_TaxID=4577; Zea mays (Maize).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Isolate United States/Kansas/1987;
RX PubMed=2726455; DOI=10.1093/nar/17.8.3163;
RA Nutter R.C., Scheets K., Panganiban L.C., Lommel S.A.;
RT "The complete nucleotide sequence of the maize chlorotic mottle virus
RT genome.";
RL Nucleic Acids Res. 17:3163-3177(1989).
RN [2]
RP IDENTIFICATION.
RX PubMed=2212985; DOI=10.1099/0022-1317-71-9-1887;
RA Riviere C.J., Rochon D.M.;
RT "Nucleotide sequence and genomic organization of melon necrotic spot
RT virus.";
RL J. Gen. Virol. 71:1887-1896(1990).
RN [3]
RP FUNCTION.
RX PubMed=27242072; DOI=10.1016/j.virusres.2016.04.024;
RA Scheets K.;
RT "Analysis of gene functions in Maize chlorotic mottle virus.";
RL Virus Res. 222:71-79(2016).
CC -!- FUNCTION: Required for cell-to-cell movement of virions in the host
CC plant together with p7a. {ECO:0000269|PubMed:27242072}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:Q89846}; Single-pass type II membrane protein
CC {ECO:0000250|UniProtKB:Q89846}.
CC -!- SIMILARITY: Belongs to the gammacarmovirus double gene block protein 2
CC family. {ECO:0000305}.
CC -!- CAUTION: This sequence initiates at a non-canonical CTG leucine codon.
CC {ECO:0000305}.
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DR EMBL; X14736; CZQ76687.1; -; Genomic_RNA.
DR RefSeq; YP_009237216.1; NC_003627.1.
DR GeneID; 2652941; -.
DR Proteomes; UP000007071; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW Signal-anchor; Transmembrane; Transmembrane helix; Transport;
KW Viral movement protein.
FT CHAIN 1..64
FT /note="p7b"
FT /id="PRO_0000455297"
FT TOPO_DOM 1..12
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q89846"
FT TRANSMEM 13..30
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 31..64
FT /note="Lumenal"
FT /evidence="ECO:0000250|UniProtKB:Q89846"
SQ SEQUENCE 64 AA; 7322 MW; 5E747935E0E928F7 CRC64;
MECVCVDSSW PQWLRNLILG ILISSILFIL TKTQDTVAVY HEPSVYSIDQ TQKFQKIDIH
NGGK