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MP2_TCV
ID   MP2_TCV                 Reviewed;          85 AA.
AC   Q7TD19; A0A024E2A8;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Double gene block protein 2;
DE            Short=DGBp2;
DE   AltName: Full=Movement protein P9;
GN   ORFNames=ORF3;
OS   Turnip crinkle virus (TCV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC   Tolivirales; Tombusviridae; Procedovirinae; Betacarmovirus.
OX   NCBI_TaxID=11988;
OH   NCBI_TaxID=3709; Brassica napus subsp. rapifera.
OH   NCBI_TaxID=5130; Hypomyces.
OH   NCBI_TaxID=180540; Moricandia arvensis (Purple mistress) (Brassica arvensis).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2718381; DOI=10.1016/0042-6822(89)90369-3;
RA   Carrington J.C., Heaton L.A., Zuidema D., Hillman B.I., Morris T.J.;
RT   "The genome structure of turnip crinkle virus.";
RL   Virology 170:219-226(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=Infectious clone UK;
RA   Ryabov E.V.;
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   TOPOLOGY.
RX   PubMed=20335263; DOI=10.1128/jvi.00125-10;
RA   Martinez-Gil L., Johnson A.E., Mingarro I.;
RT   "Membrane insertion and biogenesis of the Turnip crinkle virus p9 movement
RT   protein.";
RL   J. Virol. 84:5520-5527(2010).
CC   -!- FUNCTION: Cell-to-cell movement function. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane; Multi-pass
CC       membrane protein.
CC   -!- SIMILARITY: Belongs to the carmovirus double gene block protein 2
CC       family. {ECO:0000305}.
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DR   EMBL; M22445; AHZ65050.1; -; Genomic_RNA.
DR   EMBL; AY312063; AAP78488.1; -; Genomic_RNA.
DR   RefSeq; YP_009029987.1; NC_003821.3.
DR   PRIDE; Q7TD19; -.
DR   GeneID; 944389; -.
DR   KEGG; vg:944389; -.
DR   Proteomes; UP000007403; Genome.
DR   Proteomes; UP000009133; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..85
FT                   /note="Double gene block protein 2"
FT                   /id="PRO_0000398309"
FT   TOPO_DOM        1..2
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        3..23
FT                   /note="Helical; Note=Internal signal sequence"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        24..36
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        57..85
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   VARIANT         6
FT                   /note="V -> A (in strain: Infectious clone UK)"
FT   VARIANT         29
FT                   /note="T -> V (in strain: Infectious clone UK)"
SQ   SEQUENCE   85 AA;  9454 MW;  8B6AA27966E04592 CRC64;
     MKVLLVTGVL GLLLLIKWKS QSTSTSNQTC QCPTSPWVIY AFYNSLSLVL LLCHLIPEIK
     PIHTSYNTHD SSKQQHISIN TGNGK
 
 
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