MP2_TCV
ID MP2_TCV Reviewed; 85 AA.
AC Q7TD19; A0A024E2A8;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 33.
DE RecName: Full=Double gene block protein 2;
DE Short=DGBp2;
DE AltName: Full=Movement protein P9;
GN ORFNames=ORF3;
OS Turnip crinkle virus (TCV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC Tolivirales; Tombusviridae; Procedovirinae; Betacarmovirus.
OX NCBI_TaxID=11988;
OH NCBI_TaxID=3709; Brassica napus subsp. rapifera.
OH NCBI_TaxID=5130; Hypomyces.
OH NCBI_TaxID=180540; Moricandia arvensis (Purple mistress) (Brassica arvensis).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2718381; DOI=10.1016/0042-6822(89)90369-3;
RA Carrington J.C., Heaton L.A., Zuidema D., Hillman B.I., Morris T.J.;
RT "The genome structure of turnip crinkle virus.";
RL Virology 170:219-226(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=Infectious clone UK;
RA Ryabov E.V.;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP TOPOLOGY.
RX PubMed=20335263; DOI=10.1128/jvi.00125-10;
RA Martinez-Gil L., Johnson A.E., Mingarro I.;
RT "Membrane insertion and biogenesis of the Turnip crinkle virus p9 movement
RT protein.";
RL J. Virol. 84:5520-5527(2010).
CC -!- FUNCTION: Cell-to-cell movement function. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane; Multi-pass
CC membrane protein.
CC -!- SIMILARITY: Belongs to the carmovirus double gene block protein 2
CC family. {ECO:0000305}.
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DR EMBL; M22445; AHZ65050.1; -; Genomic_RNA.
DR EMBL; AY312063; AAP78488.1; -; Genomic_RNA.
DR RefSeq; YP_009029987.1; NC_003821.3.
DR PRIDE; Q7TD19; -.
DR GeneID; 944389; -.
DR KEGG; vg:944389; -.
DR Proteomes; UP000007403; Genome.
DR Proteomes; UP000009133; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT CHAIN 1..85
FT /note="Double gene block protein 2"
FT /id="PRO_0000398309"
FT TOPO_DOM 1..2
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 3..23
FT /note="Helical; Note=Internal signal sequence"
FT /evidence="ECO:0000255"
FT TOPO_DOM 24..36
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 57..85
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT VARIANT 6
FT /note="V -> A (in strain: Infectious clone UK)"
FT VARIANT 29
FT /note="T -> V (in strain: Infectious clone UK)"
SQ SEQUENCE 85 AA; 9454 MW; 8B6AA27966E04592 CRC64;
MKVLLVTGVL GLLLLIKWKS QSTSTSNQTC QCPTSPWVIY AFYNSLSLVL LLCHLIPEIK
PIHTSYNTHD SSKQQHISIN TGNGK