ID   MP63_MYCTO              Reviewed;         159 AA.
AC   P9WIP0; L0T8A1; O08224; P0A5Q2; P97175;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Immunogenic protein MPT63;
DE   AltName: Full=16 kDa immunoprotective extracellular protein;
DE   AltName: Full=Antigen MPT63;
DE   Flags: Precursor;
GN   Name=mpt63; OrderedLocusNames=MT1977;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; AE000516; AAK46249.1; -; Genomic_DNA.
DR   PIR; B70635; B70635.
DR   RefSeq; WP_003409684.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WIP0; -.
DR   SMR; P9WIP0; -.
DR   EnsemblBacteria; AAK46249; AAK46249; MT1977.
DR   KEGG; mtc:MT1977; -.
DR   PATRIC; fig|83331.31.peg.2128; -.
DR   HOGENOM; CLU_067309_1_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   Gene3D; 2.60.40.1240; -; 1.
DR   InterPro; IPR029050; Immunoprotect_excell_Ig-like.
DR   InterPro; IPR015250; MPT63-like.
DR   Pfam; PF09167; DUF1942; 1.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000250"
FT   CHAIN           30..159
FT                   /note="Immunogenic protein MPT63"
FT                   /id="PRO_0000427971"
SQ   SEQUENCE   159 AA;  16514 MW;  EB563E1EAABCE428 CRC64;
     MKLTTMIKTA VAVVAMAAIA TFAAPVALAA YPITGKLGSE LTMTDTVGQV VLGWKVSDLK
     SSTAVIPGYP VAGQVWEATA TVNAIRGSVT PAVSQFNART ADGINYRVLW QAAGPDTISG
     ATIPQGEQST GKIYFDVTGP SPTIVAMNNG MEDLLIWEP