MP64_MYCTO
ID MP64_MYCTO Reviewed; 228 AA.
AC P9WIN8; L0TB55; P0A5Q4; P19996;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=Immunogenic protein MPT64;
DE AltName: Full=Antigen MPT64;
DE Flags: Precursor;
GN Name=mpt64; OrderedLocusNames=MT2032;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RsiV family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK46307.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE000516; AAK46307.1; ALT_INIT; Genomic_DNA.
DR PIR; B70756; B70756.
DR RefSeq; WP_003409954.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WIN8; -.
DR SMR; P9WIN8; -.
DR EnsemblBacteria; AAK46307; AAK46307; MT2032.
DR KEGG; mtc:MT2032; -.
DR PATRIC; fig|83331.31.peg.2187; -.
DR HOGENOM; CLU_080703_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 3.90.640.20; -; 1.
DR InterPro; IPR021729; DUF3298.
DR InterPro; IPR037126; PdaC/RsiV-like_sf.
DR Pfam; PF11738; DUF3298; 1.
PE 3: Inferred from homology;
KW Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000250"
FT CHAIN 24..228
FT /note="Immunogenic protein MPT64"
FT /id="PRO_0000427972"
SQ SEQUENCE 228 AA; 24855 MW; D79850CD1907999C CRC64;
MRIKIFMLVT AVVLLCCSGV ATAAPKTYCE ELKGTDTGQA CQIQMSDPAY NINISLPSYY
PDQKSLENYI AQTRDKFLSA ATSSTPREAP YELNITSATY QSAIPPRGTQ AVVLKVYQNA
GGTHPTTTYK AFDWDQAYRK PITYDTLWQA DTDPLPVVFP IVQGELSKQT GQQVSIAPNA
GLDPVNYQNF AVTNDGVIFF FNPGELLPEA AGPTQVLVPR SAIDSMLA