MP701_ARATH
ID MP701_ARATH Reviewed; 622 AA.
AC Q9C9X0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Microtubule-associated protein 70-1;
DE Short=AtMAP70-1;
DE AltName: Full=70 kDa microtubule-associated protein 1;
GN Name=MAP70.1; OrderedLocusNames=At1g68060; ORFNames=T23K23.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], IDENTIFICATION BY MASS SPECTROMETRY, AND
RP SUBCELLULAR LOCATION.
RX PubMed=15860013; DOI=10.1111/j.1365-313x.2005.02393.x;
RA Korolev A.V., Chan J., Naldrett M.J., Doonan J.H., Lloyd C.W.;
RT "Identification of a novel family of 70 kDa microtubule-associated proteins
RT in Arabidopsis cells.";
RL Plant J. 42:547-555(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=17567681; DOI=10.1242/jcs.007393;
RA Korolev A.V., Buschmann H., Doonan J.H., Lloyd C.W.;
RT "AtMAP70-5, a divergent member of the MAP70 family of microtubule-
RT associated proteins, is required for anisotropic cell growth in
RT Arabidopsis.";
RL J. Cell Sci. 120:2241-2247(2007).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION WITH MAP70.5.
RX PubMed=20399097; DOI=10.1016/j.cub.2010.02.057;
RA Pesquet E., Korolev A.V., Calder G., Lloyd C.W.;
RT "The microtubule-associated protein AtMAP70-5 regulates secondary wall
RT patterning in Arabidopsis wood cells.";
RL Curr. Biol. 20:744-749(2010).
RN [8]
RP INDUCTION.
RX PubMed=20966154; DOI=10.1104/pp.110.163402;
RA Keech O., Pesquet E., Gutierrez L., Ahad A., Bellini C., Smith S.M.,
RA Gardestroem P.;
RT "Leaf senescence is accompanied by an early disruption of the microtubule
RT network in Arabidopsis.";
RL Plant Physiol. 154:1710-1720(2010).
CC -!- FUNCTION: Plant-specific protein that interact with microtubules. In
CC association with MAP70.5, is essential for the normal banding pattern
CC of secondary cell wall and for the proper development of xylem
CC tracheary elements and wood formation. {ECO:0000269|PubMed:20399097}.
CC -!- SUBUNIT: Interacts with MAP70.5 and itself.
CC {ECO:0000269|PubMed:20399097}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000269|PubMed:15860013, ECO:0000269|PubMed:17567681,
CC ECO:0000269|PubMed:20399097}. Cytoplasm, cytoskeleton, phragmoplast
CC {ECO:0000269|PubMed:15860013}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000269|PubMed:15860013}. Note=Associated with microtubules in
CC interphase arrays, preprophase bands, spindles, and phragmoplasts.
CC Associated with microtubules in tracheary elements.
CC {ECO:0000269|PubMed:15860013}.
CC -!- INDUCTION: Down-regulated during senescence.
CC {ECO:0000269|PubMed:20966154}.
CC -!- SIMILARITY: Belongs to the MAP70 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM086438; CAJ31078.1; -; mRNA.
DR EMBL; AC012563; AAG52019.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34742.1; -; Genomic_DNA.
DR EMBL; AY074303; AAL67000.1; -; mRNA.
DR EMBL; AY096658; AAM20292.1; -; mRNA.
DR PIR; G96703; G96703.
DR RefSeq; NP_176973.1; NM_105476.5.
DR AlphaFoldDB; Q9C9X0; -.
DR SMR; Q9C9X0; -.
DR BioGRID; 28355; 5.
DR IntAct; Q9C9X0; 7.
DR STRING; 3702.AT1G68060.1; -.
DR iPTMnet; Q9C9X0; -.
DR MetOSite; Q9C9X0; -.
DR PaxDb; Q9C9X0; -.
DR PRIDE; Q9C9X0; -.
DR ProteomicsDB; 250941; -.
DR EnsemblPlants; AT1G68060.1; AT1G68060.1; AT1G68060.
DR GeneID; 843134; -.
DR Gramene; AT1G68060.1; AT1G68060.1; AT1G68060.
DR KEGG; ath:AT1G68060; -.
DR Araport; AT1G68060; -.
DR TAIR; locus:2200306; AT1G68060.
DR eggNOG; ENOG502QTPA; Eukaryota.
DR HOGENOM; CLU_023069_0_0_1; -.
DR InParanoid; Q9C9X0; -.
DR OMA; HMRLKVL; -.
DR OrthoDB; 579471at2759; -.
DR PhylomeDB; Q9C9X0; -.
DR PRO; PR:Q9C9X0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C9X0; baseline and differential.
DR Genevisible; Q9C9X0; AT.
DR GO; GO:0010005; C:cortical microtubule, transverse to long axis; IDA:TAIR.
DR GO; GO:0009524; C:phragmoplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0008017; F:microtubule binding; IDA:TAIR.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; TAS:TAIR.
DR GO; GO:0009832; P:plant-type cell wall biogenesis; IMP:TAIR.
DR GO; GO:0010051; P:xylem and phloem pattern formation; IMP:TAIR.
DR InterPro; IPR009768; MAP70.
DR PANTHER; PTHR31246; PTHR31246; 1.
DR Pfam; PF07058; MAP70; 1.
PE 1: Evidence at protein level;
KW Cell wall biogenesis/degradation; Coiled coil; Cytoplasm; Cytoskeleton;
KW Microtubule; Reference proteome.
FT CHAIN 1..622
FT /note="Microtubule-associated protein 70-1"
FT /id="PRO_0000409457"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..483
FT /note="Required for targeting to microtubules"
FT REGION 388..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 66..365
FT /evidence="ECO:0000255"
FT COILED 541..590
FT /evidence="ECO:0000255"
FT COMPBIAS 388..457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..593
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 69290 MW; 65E70B259001F692 CRC64;
MSDVSADGGF LSAEQATTPV AIPTPYPSLT VSASYKEKSS GRRRPVRPSF DAAADNEFIT
LLHGSDPVKV ELNRLENEVR DKDRELSEAN AEIKALRLSE RQREKACEEL TDELAKLDGK
LKLTESLLQS KNLEIKKINE EKKASMAAQF AAEATLRRVH AAQKDDDMPP IEAILAPLEA
ELKLARSEIG KLQEDNRALD RLTKSKEAAL LDAERTVETA LAKAALVDDL QNKNQELMKQ
IEICQEENKI LDRMHRQKVA EVEKLTQTVR ELEEAVLAGG AAANAVRDYQ RKFQEMNEER
KTLDRELARA KVTANRVATV VANEWKDGND KVMPVKQWLE ERRFLQGEMQ QLRDKLAISD
RAAKSEAQLK DKFQLRLRVL EETLRGTSSI SIRNTPEGRS MSNGPSRRQS IGGSDNLQKF
ASNGFLSKKT PMRNSFTSNS TSVLKNAKGT SKSFDGGTRS LDRGKALLKG PGNYSFNKAC
DETKESESPN TWKEDSEEKP PSELPAPATE DNVPGVLYDL LQKEVVALRK SSHEKDQSLK
DKDDAIEMLA KKVETLTKAM EVEAKKMRRE VAAMEKEVAA MRVDKDQDNR AKRSSNTKPS
SNTAQILAAR AAGRSGLTRS TQ
