MP703_ARATH
ID MP703_ARATH Reviewed; 629 AA.
AC Q9ZUA3;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Microtubule-associated protein 70-3;
DE Short=AtMAP70-3;
DE AltName: Full=70 kDa microtubule-associated protein 3;
GN Name=MAP70.3; OrderedLocusNames=At2g01750; ORFNames=T8O11.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=15860013; DOI=10.1111/j.1365-313x.2005.02393.x;
RA Korolev A.V., Chan J., Naldrett M.J., Doonan J.H., Lloyd C.W.;
RT "Identification of a novel family of 70 kDa microtubule-associated proteins
RT in Arabidopsis cells.";
RL Plant J. 42:547-555(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Plant-specific protein that interact with microtubules.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC Note=Associated to microtubules.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9ZUA3-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the MAP70 family. {ECO:0000305}.
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DR EMBL; AM086440; CAJ31080.1; -; mRNA.
DR EMBL; AC006069; AAD12697.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05492.1; -; Genomic_DNA.
DR PIR; F84428; F84428.
DR RefSeq; NP_178284.1; NM_126236.4. [Q9ZUA3-1]
DR AlphaFoldDB; Q9ZUA3; -.
DR SMR; Q9ZUA3; -.
DR STRING; 3702.AT2G01750.2; -.
DR iPTMnet; Q9ZUA3; -.
DR PaxDb; Q9ZUA3; -.
DR PRIDE; Q9ZUA3; -.
DR ProteomicsDB; 238266; -. [Q9ZUA3-1]
DR EnsemblPlants; AT2G01750.1; AT2G01750.1; AT2G01750. [Q9ZUA3-1]
DR GeneID; 814705; -.
DR Gramene; AT2G01750.1; AT2G01750.1; AT2G01750. [Q9ZUA3-1]
DR KEGG; ath:AT2G01750; -.
DR Araport; AT2G01750; -.
DR eggNOG; ENOG502QTPA; Eukaryota.
DR InParanoid; Q9ZUA3; -.
DR OMA; NWKANAE; -.
DR PhylomeDB; Q9ZUA3; -.
DR PRO; PR:Q9ZUA3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZUA3; baseline and differential.
DR Genevisible; Q9ZUA3; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR InterPro; IPR009768; MAP70.
DR PANTHER; PTHR31246; PTHR31246; 1.
DR Pfam; PF07058; MAP70; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Cytoplasm; Cytoskeleton; Microtubule;
KW Reference proteome.
FT CHAIN 1..629
FT /note="Microtubule-associated protein 70-3"
FT /id="PRO_0000409459"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..493
FT /note="Required for targeting to microtubules"
FT /evidence="ECO:0000250"
FT REGION 391..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..519
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 578..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 75..375
FT /evidence="ECO:0000255"
FT COILED 544..592
FT /evidence="ECO:0000255"
FT COMPBIAS 15..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..629
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 69772 MW; B561D0F8DE0A9858 CRC64;
MEEGGYAFEV NNGRPTASEF GTTARISSPS LTMSSSFREG GGGGGSKGLT RRRSMKPSFD
ADNEFITLLH GSDPVKVELN RLENDVRDKD RELSESQAEI KALRLSERQR EKAVEELTEE
LGKMSEKLKL TENLLDSKNL EIKKINEEKR ASMAAQFAAE ATLRRVHAAQ KDDDMPPIEA
ILAPLEAELK LARHEIVKLQ DDNRALDRLT KSKEAALLDA ERTVQSALAK ASMVDDLQNK
NQELMKQIEI CQEENRILDK LHRQKVAEVE KFTQTVRELE EAVLAGGTAA NAVRDYQRKF
QEMNEERRIL DRELARAKVS ASRVATVVAN EWKDGSDKVM PVKQWLEERR FLQGEMQQLR
DKLAIADRAA KSEAQLKEKF QLRLRVLEES LRGPSSSGNR STPEGRSMSN GPSRRQSLGG
ADIIPKLTSN GFFSKRSPSS QFRSLNASTS TILKHAKGTS RSFDGGSRSL DRSKVLTNEP
RSKFPLNQSS EGTSGGGSPN STKQGDSEKA AGTNNDSVPG VLHDLLQKEV ITLRKAANDK
DQSLRDKDEA IEMLAKKVET LTKAMEVEAK KMRREVAAME KEVSAMRVDN KGSDSRTRRH
STNSKGASTT AQLLSGRGSG RMGMTRSTQ
