MP704_ARATH
ID MP704_ARATH Reviewed; 604 AA.
AC Q9LQU7; Q944R5;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Microtubule-associated protein 70-4;
DE Short=AtMAP70-4;
DE AltName: Full=70 kDa microtubule-associated protein 4;
GN Name=MAP70.4; OrderedLocusNames=At1g14840; ORFNames=F10B6.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=15860013; DOI=10.1111/j.1365-313x.2005.02393.x;
RA Korolev A.V., Chan J., Naldrett M.J., Doonan J.H., Lloyd C.W.;
RT "Identification of a novel family of 70 kDa microtubule-associated proteins
RT in Arabidopsis cells.";
RL Plant J. 42:547-555(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Plant-specific protein that interact with microtubules.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC Note=Associated to microtubules.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9LQU7-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the MAP70 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL11578.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AM086441; CAJ31081.1; -; mRNA.
DR EMBL; AC006917; AAF79237.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29233.1; -; Genomic_DNA.
DR EMBL; AF424584; AAL11578.1; ALT_SEQ; mRNA.
DR EMBL; BT002258; AAN72269.1; -; mRNA.
DR PIR; C86282; C86282.
DR RefSeq; NP_563959.1; NM_101353.2. [Q9LQU7-1]
DR AlphaFoldDB; Q9LQU7; -.
DR SMR; Q9LQU7; -.
DR iPTMnet; Q9LQU7; -.
DR PaxDb; Q9LQU7; -.
DR PRIDE; Q9LQU7; -.
DR EnsemblPlants; AT1G14840.1; AT1G14840.1; AT1G14840. [Q9LQU7-1]
DR GeneID; 838049; -.
DR Gramene; AT1G14840.1; AT1G14840.1; AT1G14840. [Q9LQU7-1]
DR KEGG; ath:AT1G14840; -.
DR Araport; AT1G14840; -.
DR TAIR; locus:2006787; AT1G14840.
DR eggNOG; ENOG502QTPA; Eukaryota.
DR HOGENOM; CLU_023069_0_0_1; -.
DR InParanoid; Q9LQU7; -.
DR OMA; NHHSSEG; -.
DR PhylomeDB; Q9LQU7; -.
DR PRO; PR:Q9LQU7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LQU7; baseline and differential.
DR Genevisible; Q9LQU7; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; ISS:TAIR.
DR GO; GO:0008017; F:microtubule binding; ISS:TAIR.
DR GO; GO:0007010; P:cytoskeleton organization; TAS:TAIR.
DR InterPro; IPR009768; MAP70.
DR PANTHER; PTHR31246; PTHR31246; 1.
DR Pfam; PF07058; MAP70; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Cytoplasm; Cytoskeleton; Microtubule;
KW Reference proteome.
FT CHAIN 1..604
FT /note="Microtubule-associated protein 70-4"
FT /id="PRO_0000409460"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..470
FT /note="Required for targeting to microtubules"
FT /evidence="ECO:0000250"
FT REGION 367..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 49..351
FT /evidence="ECO:0000255"
FT COILED 521..569
FT /evidence="ECO:0000255"
FT COMPBIAS 459..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 604 AA; 67488 MW; EF6E1205E847EDF1 CRC64;
MEERGFMSPS LAISASYREG GSKGMSRRRS MRPSFDADNE FMNLLHGSDP VRIELNRLEN
EVRDKDRELS EGQAEIKALR LSERQREKAV EELTEELGKM AEKLKLIENL LESKNLEIKK
INEEKKASMA AQFAAEASLR RVHAAQKDDD MPPIEAILAP LEAELKLSRQ EIAKLQDDNK
SLDRLTKSKE AALLDAERTV QSALAKASMV DDLQNKNQEL MKQIEICQEE NRIIDKMHRQ
KVAEVEKLMQ SVRELEEAVL AGGAAANAVR DYQRKFQEMN EERKILEREL ARAKVNANRV
ATVVANEWKD SNDKVMPVRQ WLEERRFLQG EMQQLRDKLA IADRAAKSEA QLKEKFLLRL
RVLEESLKGP TSSSSRGTSV GRSSSNGPTR RQSLGGAETS PKITSNGSLI KRTPSSQLRS
LTASASTVLK HAKGTSRSFD GGTRSLDRSK VLINGPRSNF PLNHKSSEGT SRGESPSSIK
GEEESADKAT NNDSVPGVLY DLLQKEVITL RKAAHEKDQS LRDKDEAIEM LAKKVETLTK
AMDVEAKKMR REVAVMGKEV AAMRVVDKGQ QDSKTRRLSV SKGNTAQLLS GRVSGRIGMT
RSTQ
